Kaer Biotherapeutics Corporation

Cytoptics Corporation

Guanglin Li

Donovan B Yeates

Lid B Wong

Tarun Chandra

Mahandas A Kizhakayil

Jinghai Yi

Donovan Yeates

A system and method that can simultaneously acquire electrocardiogram or pulse rate data (), dynamically perform time-frequency () and chaotic analysis () in real-time, visually display the results in a convenient graphical format () and store the results in a computer file format ().

Instantaneous autonomic nervous function and cardiac predictability based on heart and pulse rate variability analysis

A method and system is disclosed which is capable of delivering at a high dose rate, respirable solid aerosols derived from aqueous- or nonaqueous-based solutions containing the desired therapeutic agent(s). The method and system comprises the integration of an aerosol generator, an aerosol evaporator, an aerosol concentrator, and an aerosol flow regulator. The aerosol generator generates 10-30 &#x3bc;m droplets, with a narrow size distribution. The aerosol jet is arrested by a coaxial counter-flow heated air jet, and evaporated rapidly by annular swirling heated air. Most of the air, together with the unwanted solvent vapor, is removed from the aerosol stream during the process of aerosol concentration. The output aerosol carries the dry particles to be inhaled by the patient. The respiratory-governed control of aerosol fluid generation system delivers fluid containing the test agent of interest (drug or toxin) to the aerosol generator throughout inhalation.

Aerosol processing and inhalation method and system for high dose rate aerosol drug delivery

Growing community of inventors

Chicago, IL, United States of America

Guanglin Li