Hitachi, Ltd.

Hitachi High-tech Corporation

Hitachi Industrial Equipment Systems Co., Ltd.

Guangbin Zhou

Masaharu Kiyama

Takayuki Nozaki

Ryota Nakajima

Shizu Matsuoka

Masakazu Sugaya

Koichi Terada

Taku Nakamura

Shizu Takeda

Daisuke Suzuki

Midori Kato

Hikaru Saito

Hiroshi Suzuki

Satoru Kaneko

Yoshitaka Iwaji

Kazuhiro Tanaka

Kazuaki Tobari

Taizo Miyazaki

Hiroko Hanzawa

Toyoshige Kobayashi

Kenichi Minami

Naoko Senda

Gorou Yoshida

Yumiko Igarashi

Kunio Ohyama

Ryota Kajima

Nozaki Takayuki

The present invention accurately estimates the opening state of a solenoid valve using a feature amount based on driving current information of the solenoid valve. A solenoid valve abnormality detection device, which uses a driving current pattern associated with valve opening of a solenoid valve and detected by a current sensor to detect an abnormality of the solenoid valve, comprises: a feature amount extraction unit that determines a feature amount of a driving current pattern associated with valve opening of the solenoid valve within a predetermined detection period; a feature amount correction unit that estimates the valve temperature of the solenoid valve; and an opening state estimation unit that estimates the opening state of the solenoid valve using the feature amount value corrected by the feature amount correction unit.

Solenoid valve abnormality detection device, automatic medical analysis apparatus using same, and solenoid valve abnormality detection method

A liquid feed device that feeds a liquid medium and a cell suspension to target containers by respectively suited liquid feed methods is provided. A pumpis connected between a first liquid bottlecontaining a liquid medium and a second liquid bottlecontaining a cell suspension, and a receptacleto be used as a culture container is connected downstream of a second liquid bottle. The liquid medium in the first liquid bottle is sent to the receptacle through the pumpand a branch pointby opening a first supply valve, and the cell suspension in the second liquid bottle is sent to the receptacle by opening a first gas introducing valve, a second gas introducing valve, and a second supply valveand transferring, by pressure, a gas supplied from the first gas introducing valveto the second liquid bottle through the pumpand a branch point

Liquid feed device, and cell culture device and method using same

An induction motor overheat monitoring method and device detects overheating of an induction motor from a detection value of a current sensor. A resistance calculation relationship data indicating a relationship between a resistance and a feature amount at the time of starting of the induction motor and a determination reference value for determining overheating are stored in advance. At each starting, a current of the induction motor is detected, a signal regarding a phase angle difference is calculated, and a feature amount of the motor is calculated from the signal regarding the phase angle difference. Further, a resistance of the induction motor is calculated by using the feature amount of the motor and the resistance calculation reference data stored in advance. Then, a temperature of the induction motor is calculated from the resistance of the induction motor, and it is determined if the motor is overheated.

Induction motor overheat monitoring method, induction motor monitoring device, and induction motor control system

A liquid delivery device includes a first and second container for a first and second liquid; a third container for receiving a first and second liquid; a fourth container into which a first and second liquid are discharged; a fifth container for a third liquid; a first liquid delivery tube for delivering a first liquid; a second liquid delivery tube for delivering a second liquid; a third liquid delivery tube connected to the first and second liquid delivery tube; a first liquid delivery pump on the third liquid delivery tube; a fourth liquid delivery tube for discharging a first liquid contained in the third container and delivering a third liquid to the third container; a fifth liquid delivery tube connected to the fourth liquid delivery tube; a sixth liquid delivery tube connected to the fourth liquid delivery tube; and a second liquid delivery pump on the fourth liquid delivery tube.

Liquid delivery device and cell culture device using the same

Maintaining pressure inside a culturing vessel is difficult when minimizing the size of a liquid supply path that supplies liquid and gas to a cell culturing vessel that performs two-level culturing (co-culturing). This cell culturing device includes: culturing vessels; a flow path having at least first supply ports capable of supplying liquid or gas to the culturing vessels and first discharge ports that discharge the gas from the culturing vessels, said flow path discharging gas from the first discharge ports to the atmosphere; and a filter in the flow path. A trap bottle is provided between the first discharge ports and the filter upon the flow path to collect moisture from the discharged gas. Thus, a liquid phase and a gas phase are separated in the trap bottle; moisture is prevented from reaching the filter; filter clogging is prevented; and the internal pressure of the culturing vessels can be maintained.

Cell culturing device

The purpose of the present invention is to provide a valve mechanism which features a simple structure adapted to collectively control the supply of gas or culture medium to a plurality of cultivation containers for simultaneous cultivation and to enhance the reliability of the valve mechanism. The valve mechanism of the invention is a valve mechanism for opening and closing passages for liquid or gas. The valve mechanism includes: clip members adapted to close a plurality of tube passages, respectively; a multiple cam member for opening the clip members in sequence by making contact with the clip members; and a rotational mechanism for rotating the multiple cam member. The clip member includes: a spring for closing a clip thereof; and a clip contact portion for a cam contact portion of the multiple cam member to make contact therewith.

Valve mechanism, cell cultivation apparatus using same, and cell cultivation method

There is the problem that a liquid culture medium fed by a pump has a high frequency of contact with a gas during movement in a tube, and the pH value of the liquid culture medium before and after feeding changes easily. In a liquid feeder and a cell culture apparatus provided therewith, a feed pipeis connected with a gas bag, the liquid to be fed into the feed pipeis fed so as to be sandwiched by a gas for suppressing the qualitative changes of the liquid. Furthermore, the gas bag is connected with a containerfor holding a liquid, and holds the gas for suppressing qualitative changes of the liquid in a gas phase of the container.

Liquid feeding device and cell culture device

The liquid feeder includes a liquid feeding pipe having a liquid introduce port and a liquid discharge port, a housing container which holds liquid to be introduced from the liquid introduce port, a liquid feed mechanism which feeds the liquid in the liquid feeding pipe to the liquid discharge port, a gas introduce unit which introduces gas into the liquid feeding pipe, and a liquid level detection unit which detects an advancing liquid level of the liquid to be fed in the liquid feeding pipe. The gas introduce unit is connected to a branch part provided in the liquid feeding pipe on the upstream side of the liquid feed mechanism. The liquid level detection unit is provided on the downstream side of the branch part.

Liquid delivery device and cell culture device using same

An automatic culture device which employs closed-system culture vessels and in which, when a passage part () and a rotational valve mechanism () are configured, the multiple culture vessels in a culture vessel part () can be rendered equal in liquid-feeding conditions by, for example, regulating the length of each passage. As a result, the evenness in quality of cells incubated in the multiple culture vessels is rendered possible. Furthermore, by providing a mechanism which enables a user to normally set passages in the device, the evenness in quality of the cells is rendered possible likewise.

Cell culture device

In culture vessels for producing biological samples, it is possible to prevent decrease in a temperature at the time of taking out the culture vessels from an automatic culture apparatus and during delivery of the culture vessels which have been taken out from the automatic culture apparatus. This invention includes a culture vesselholding a biological sample therein, a heat storage portionholding the culture vessel, and a heat insulation portionsurrounding the heat storage portion. The whole circumference or a part of, andof the heat insulation portionis removable depending on an arrangement environment.

Cell culturing device, culturing vessel, and holding vessel

Provided is a cell culturing vessel for holding and culturing cells. It has a first vessel that stores a culture medium and cells or only a culture medium, a second vessel that is placed above the first vessel and stores a culture medium and cells or only a culture medium, a main vessel that holds the first vessel and houses the second vessel, and a lid member that engages with the main vessel. The main vessel has a pressing member that fixes and holds the first vessel in the main vessel and the second vessel is eccentrically held in the first vessel by the pressing member.

Cell-culturing vessel and cell-culturing device using same

Disclosed is a cell culture vessel of the present invention, which is composed of a space enclosed by a housing that supports a medium and a cell attachment part, disposed on the bottom surface of the space, that attaches and supports the cells, the cell attachment part having a cell immobilizing mechanism that guides the cells in the space to the cell attachment part to immobilize there and a cell detachment mechanism that detaches the cells attached in the cell attachment part, the cell immobilizing mechanism having a step of applying a voltage to an electrode disposed in the cell attachment part to generate a heterogeneous electric field in the space, and the cell detachment mechanism having a step of applying a voltage to an electrode disposed in the cell attachment part to induce electrolyte in the space.

Growing community of inventors

Tokyo, Japan

Guangbin Zhou