Sk Chemicals Co., Ltd.

Sam Chun Dang Pharm. Co., Ltd.

In2gen Co., Ltd.

Hoon Cha

Won-son Choi

Ltd. In2gen Co.

Suk Ho Lee

Tae Kon Kim

Nam Kyu Lee

Ju Young Lee

Guang-jin Im

Je Ho Ryu

Nam-ho Kim

Jae-sun Kim

Jin-young Choi

Guang-Jin Im

Jae-Sun Kim

Dae-Kee Kim

Chang-Kyun Han

Wie-Jong Kwak

Jung-Woo Seo

Bongcheol Kim

Soomin Lee

Se Jun Yun

Wonrack Choi

Jin Young Choi

Nam Ho Kim

Junwon Lee

Byung-Jhip Ha

Na-Won Park

Young-Jue Bang

Nam-Ho Kim

Jin-Young Choi

Won-Son Choi

Yong-Seop Park

Chil Mann Jung

Do Hyun Ryu

ChilMann Jung

Tae Kon 348-11 Hyundai Byeoksan Apt 886-1 Kim

Chilmann C-103 Milae House Jung

Bong Cheol Kim

Provided is an ophthalmic pharmaceutical composition having a certain pH, comprising aflibercept as an active ingredient and an acetate salt buffering agent, wherein the composition is free of an ionic tonicity agent, remarkably reduces the formation of dimeric and multimeric impurities, and maintains the biological activity in a high level for a long time, under the accelerated and stress conditions as well as under the cold storage condition.

Aflibercept ophthalmic pharmaceutical composition

The present invention relates to the triterpene compounds improving in brain functions. In particular, the present invention relates to a novel use of the triterpene compounds represented by the Formula 1 for improving decreased memory and a pharmaceutical composition for improving brain functions comprising the triterpene compounds represented by the Formula 1.

Triterpene compounds which are effective on improvement of brain function

This invention relates to Pulsatillae Radix extract for improving brain functions. More specifically, this invention relates to Pulsatillae Radix extract, its active fractions and a pharmaceutical product and a health food containing the same respectively having a protective activity against neurotoxicity and a growth inhibitory effect induced by beta-amyloid, an anti-oxidizing effect, a neuron proliferating effect and improving memory thereby effective in improving brain functions such as Mild Cognitive Impairment and dementia.

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Disclosed are agents that inhibit histone deacetylase. More specifically, the present invention relates to novel hydroxamic acid derivatives or pharmaceutically acceptable salts thereof for anticancer agents or other therapeutic agents based on their histone deacetylase inhibitory activity.

&#x3b1;,&#x3b2;-unsaturated hydroxamic acid derivatives and their use as histone deacetylase inhibitors

The invention relates to a series of pyrrolopyrimidinone derivatives of the formula ():

Pyrrolopyrimidinone derivatives, process of preparation and use

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Ansan-si, South Korea

Guang-Jin Im