University of Michigan

Guan Xu

Paul Langford Carson

Xueding Wang

Cheri Deng

Hakan Demirci

A method of diagnosing intraocular tumors including illuminating a tissue sample using a pulsed light source resulting in output of heat and thermoelastic expansion of the tissue sample. The thermoelastic expansion of the tissue sample produces propagating waves in ultrasonic frequencies. The propagating waves are acquired using an ultrasound system and back-projection reconstruction, thereby mapping anatomies with optical contrast at ultrasonic resolution to image intraocular tumors.

Method of photoacoustic imaging intraocular tumors including back-projection reconstruction to measure heterogeneity

A method of performing a photoacoustic physio-chemical analysis is provided. The method includes performing one or more photoacoustic scans on a tissue to generate a plurality of photoacoustic signals. The photoacoustic signals are transformed into a frequency domain to form a power spectra. The method also includes generating a two dimensional (2D) physio-chemical spectrogram from the power spectra. A probe for performing a photoacoustic physio-chemical analysis is also provided.

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Ann Arbor, MI, United States of America

Guan Xu