Abbott Cardiovascular Systems, Inc.

Advanced Cardiovascular Systems, Inc.

Gregory Waimong Chan

Mina W Chow

Srinivasan Sridharan

Jessica G Chiu

Nianjiong Joan Bei

Hongzhi Bai

Mark J Bly

William E Webler, Jr

Shubhayu Basu

William Earl Webler, Jr

Randolf Von Oepen

Kevin Joe Ehrenreich

Travis Richard Yribarren

Jesus Magana

Rommel Lumauig

Binh T Nguyen

Douglas H Gesswein

Lorcan James Coffey

Robert C Esselstein

Stephen G Schaible

Gabriel Asongwe

Fernando Gonzalez

Dwight A Ambat

Yan Shen

Thomas Ray Hatten

Sung Woo Min

Manolo Lumauig

Tom Hatten

Thuhuong Thi Phan

John Francis Boylan

Sungwoo Min

Barbara E Stamberg

William Jason Fox

Laura Melton Kalvass

Carol M Lee

Methods and compositions for treating post-myocardial infarction damage are herein disclosed. In some embodiments, a carrier with a treatment agent may be fabricated. The carrier can be formulated from a bioerodable, sustained-release substance. The resultant loaded carrier may then be suspended in at least one component of a two-component matrix system for simultaneous delivery to a post-myocardial infarction treatment area.

Methods and compositions for treating post-cardial infarction damage

An endoprosthesis for treating a bifurcated lumen. The distal end of the endoprosthesis can include at least two wings and at least two troughs so the endoprosthesis can adequately scaffold the ostium of a bifurcated lumen by at least partially straddling the carina of the lumen bifurcation. The distal end of the endoprosthesis can also be configured to have increased expandability to help allow conformity to the anatomy of a bifurcated lumen.

Expandable endoprostheses, systems, and methods for treating a bifurcated lumen

Embodiments include an infusion-occlusion system having a delivery catheter, a guide catheter adapted to receive the delivery catheter, and a guidewire with an occlusion device adapted to be received within the guide catheter. The guide catheter of the catheter kit may be provided with an occlusion device at the distal end of the guide catheter. The delivery catheter may have an accessory lumen, coaxial or co-linear lumen, a supporting mandrel, or an occlusion device at its distal end. Moreover, according to some embodiments, occlusion devices may be a single material or a composite balloon having an inner liner and an outer layer of different materials, a high compliance low pressure balloon, or a filter device that restricts particles from passing through but does not restrict fluid, such as blood. An inflation device with a large volume and low volume syringe can be used to inflate the balloon.

Infusion treatment agents, catheters, filter devices, and occlusion devices, and use thereof

A catheter for delivering an agent to an injection site in a wall of a patient's body lumen, with an elongated shaft having a needle-through lumen slidably containing a needle therein, and an expandable member on the distal shaft section which has a collapsed configuration and a radially expanded configuration. In the radially expanded configuration, the expandable member supports the shaft in a position spaced away from the body lumen wall, and the needle slidably exits the needle-through lumen in the extended configuration through the port spaced away from the body lumen wall as a portion of the expandable member maintains the position of the port section of the shaft in the body lumen. The expandable member typically has an open-walled, helical, or lobed configuration providing a perfusion path along the expandable member.

Agent delivery catheter having a radially expandable centering support member

A delivery catheter that includes a flexible shaft having a proximal end and a distal end, the distal end having an outer diameter less than about 13 mm; a delivery lumen having a proximal end and a distal end, the delivery lumen within the flexible shaft, the delivery lumen having at least an outlet port or at least one side hole at the distal end of the delivery lumen, the delivery lumen having a cross-sectional area at least about 5 mm; a pressure monitoring lumen having a proximal end and a distal end, the pressure monitoring lumen within the flexible shaft; a pressure port adjacent to and connected to the distal end of the pressure monitoring lumen; a balloon inflation lumen having a proximal end and a distal end, the balloon inflation lumen within the flexible shaft; a soft tip at the distal end of the flexible shaft; a balloon at the distal end of the flexible shaft, the balloon connected to the distal end of the balloon inflation lumen, the balloon includes at least one of the following materials, polyether block amide resin, polyetheramide, polyurethane, silicone, natural latex, or synthetic latex; wherein the balloon is adapted to inflate to a diameter range of about 4 to about 15 mm.

Retrograde pressure regulated infusion

An apparatus including an expandable body; at least one delivery cannula coupled to an exterior portion of the expandable body; a needle having a protuberance thereon disposed in a lumen of the at least one delivery cannula; a stop disposed in the lumen of the at least one delivery cannula at a position distal to the protuberance on the needle. A method including positioning a catheter assembly including at least one needle delivery device disposed in an at least one delivery cannula, the at least one delivery cannula having an exit end; modifying the shape of the catheter assembly to modify the orientation of the exit end of the at least one delivery cannula at a region of interest; and advancing the at least one needle delivery device beyond the exit end of the at least one delivery cannula according to a controlled orientation.

Needle catheter

Delivery system for delivery of a medical device includes an inner member having a proximal section, a distal section and a longitudinal axis therebetween. The inner member has a first layer and a second layer wherein the first layer and the second layer are attached together at a first segment and a second segment. The second segment is spaced from the first segment along a length of the inner member and the first layer and the second layer are free of attachment between the first segment and the second segment. The inner member further includes at least two wires disposed along the length of the inner member between the first layer and the second layer. As disclosed, the at least two wires can include a first coil and a second coil moveable relative to each other between the first and second segments.

Rapid-exchange retractable sheath self-expanding delivery system with incompressible inner member and flexible distal assembly

Agent delivery catheter having a radially expandable centering support members

Methods and apparatus for delivering a treatment agent through a percutaneous delivery apparatus are herein disclosed. In some embodiments, an apparatus can include an expandable body with at least one delivery cannula having a lumen therethrough coupled to an exterior portion of the expandable body. The expandable body can be coupled to a delivery assembly with a hub. The delivery cannula can house at least one needle with a protuberance on a distal end. A portion of the hub can house at least one needle with a protuberance on a proximal end. In some embodiments, the protuberance (proximal or distal) can direct the orientation of the needle during an application of treatment agent. In some embodiments, the delivery cannula can include at least one stop for controlling the movement of the needle during an application of treatment agent. In some embodiments, a sheath can be disposed around the delivery cannula.

Modified needle catheter for directional orientation delivery

Growing community of inventors

San Francisco, CA, United States of America

Gregory Waimong Chan