The United States of America, As Represented by the Secretary, Department of Health and Human Services

Midwest Research Institute

Spirogen Limited

Starks Associates Inc.

Gregory Turner

Philip Wilson Howard

David Edwin Thurston

Paul S Liu

B Rao Vishnuvajjala

Kenneth M Snader

Luke Y Hsiao

B Rao Vishnuvaijala

Disclosed are compounds of Formula I wherein X, Y, R-R, T, T, Z, and p are as described herein; a pharmaceutical composition comprising a compound of Formula I and a carrier; a method of inhibiting growth of a cell, which method comprises administering in an amount effective to inhibit growth a compound of Formula I; a method of treating cancer in a mammal, which method comprises administering in an amount effective to treat cancer a compound of Formula I; a method of treating a viral, parasitic, or bacterial infection of a cell, which method comprises administering in an amount effective to treat a viral, parasitic, or bacterial infection a compound of Formula I; and a method of preparing a compound of Formula I as described herein.

Pyrrolobenzodiazepine derivatives, compositions comprising the same and methods related thereto

Disclosed are compounds of Formula (I) wherein X, Y, Ri-R, T, T, Z, and p are as described herein; a pharmaceutical composition comprising a compound of Formula (I) and a carrier; a method of inhibiting growth of a cell, which method comprises administering in an amount effective to inhibit growth a compound of Formula (I); a method of treating cancer in a mammal, which method comprises administering in an amount effective to treat cancer a compound of Formula (I); a method of treating a viral, parasitic, or bacterial infection of a cell, which method comprises administering in an amount effective to treat a viral, parasitic, or bacterial infection a compound of Formula (I); and a method of preparing a compound of Formula (I) as described herein. 

Growing community of inventors

Independence, MO, United States of America

Gregory Turner