Colgate Palmolive Company

Siltech Corporation

Brigham Young University

Gregory Szewczyk

Lyndsay Schaeffer-Korbylo

Suzanne Jogun

Evangelia Arvanitidou

Michael Prencipe

Ravi Subramanyam

Long Pan

Laurence Du-Thumm

Andre Morgan

David F Suriano

Jason Nesta

Viktor Dubovoy

Lisa Manus

Karen L Wisniewski

Venda Porter Maloney

Gary J Jakubicki

Sarita Vera Mello

Rensl Dillon

Davide Miksa

Daniel Smith

Anthony J O'Lenick, Jr

Suman Kumar Chopra

Harsh Mahendra Trivedi

Barbara J Thomas

Sharon Kennedy

Ammanuel Mehreteab

Lynette Anne Zaidel

Joan Gambogi

Guisheng Pan

Paloma Pimenta

Zhigang Hao

Shiri Nawrocki

Joe Vazquez

Neeta Atul Patel

Cynthia McCullar Murphy

Baohua Qiao

Julie Burke

Kimdra Smith-Webster

Christine Cuiule

Catherine Lewus

Caryn R Westphal

Marian N Holerca

Kevin Mark Kinscherf

Carl Myers

Zhi Lu

Xiang Chen

Betty Won

Shashank Vishwanath Potnis

Andrei Potanin

Nihal Dogu

Nora Lin

Melissa Muir

Kurt T Sackariasen

Rick Vrckovnik

Mark Riddle

Alexander James Mijalis

Amy Engels

Lauren Evans

Dipak Patel

David Frank Suriano

Andre' Michelle Morgan

Caryn Westphal

Laurence D Du-Thumm

Andre M Morgan

Nora C Lin

Anthony J O'lenick

Satish Bulsara

Andre Michelle Morgan

Evangelia S Arvanitidou

Cynthia Mccullar Murphy

Philip Anthony Gorlin

Petra Archibald

Melissa A Martinetti

Shashank Potnis

An oral care composition having a soluble zinc polyphosphate complex made by combining ingredients including an inorganic zinc salt, and a plurality of long chain polyphosphates having 6 or more phosphate polymer units, the relative amount of inorganic zinc salt and long chain polyphosphates providing a phosphorus to zinc mole ratio of at least 6:1. Further provided is a method of treating a subject suffering from dentinal sensitivity applying the oral care composition to the teeth and gums of the subject.

Zinc phosphate complex for oral care

A soluble zinc polyphosphate complex made by combining ingredients which include an inorganic zinc salt and a plurality of long chain polyphosphates having 6 or more phosphate polymer units, the relative amount of inorganic zinc salt and long chain polyphosphates providing a phosphorus to zinc mole ratio of at least 6:1. Further provided is a method of making this soluble zinc polyphosphate.

Zinc phosphate complex

An oral care composition having a soluble zinc polyphosphate complex made by combining ingredients including a zinc salt, a plurality of long chain polyphosphates having 6 or more phosphate polymer units, and a solvent, the relative amount of organic zinc salt and long chain polyphosphates provides a phosphorus to zinc mole ratio of at least 6:1. Further provided is a method of treating a subject suffering from dentinal sensitivity applying the oral care composition to the teeth and gums of the subject.

A soluble zinc polyphosphate complex made by combining ingredients which include an organic zinc salt and a plurality of long chain polyphosphates having 6 or more phosphate polymer units, the organic zinc salt and long chain polyphosphates being mixed in amounts that provide a phosphorus to zinc mole ratio of 15:1 to about 55:1. Further provided is a method of making this soluble zinc polyphosphate.

An oral care composition comprising a surfactant having formula [R(OCH)OSO]M wherein R is a saturated or unsaturated alkyl group with an alkyl chain length of 8 to 30 carbon atoms; x is from 0 to 10; and M is a divalent metal cation selected from zinc cations, copper cations and stannous cations is provided.

Oral care compositions

Disclosed herein are dentifrices comprising a zinc-amino acid complex together with a thickening system comprising a non-ionic thickening agent, which have a pH greater than 8.0. Methods of using the dentifrices are also provided.

Dentifrice comprising zinc-amino acid complex

Provided herein is a method for determining the bioavailability of a metal ion in a composition comprising a source of the metal ion, wherein the metal ion has antimicrobial activity, and wherein the method comprises: a) incubating a sample of the composition with bacterial cells, and b) determining the viability of the bacterial cells after incubation. The method is useful for determining the effect of agents on the bioavailability of metal ions in a composition.

Bioavailability of metal ions

Disclosed herein are dentifrices comprising a zinc amino acid complex together with soluble phosphate salts. Methods of making and using the dentifrices are also provided.

Dentifrice compromising zinc-amino acid complex and phosphates

Disclosed herein are oral care compositions comprising a zinc amino acid halide complex, and a humectant system comprising polyethylene glycol and propylene glycol as structuring humectants, which compositions have improved rheological stability. Methods of making and using the compositions are also provided.

Rheological stabilization through mixed humectant systems in a zinc toothpaste

Described herein are oral compositions comprising a film, wherein the film comprises a dye entrapped in a silica sol-gel.

Film compositions for oral use

Dentifrice Comprising Zinc-Amino Acid Complex and Phosphates

Surface staining can be minimized or eliminated by providing an oral care composition comprising a first film comprising a pigment; and optionally a second film; wherein the first film has a dissolution rate in aqueous media that is inversely proportional to its thickness, wherein the first film is in the form of a particle.

Oral care compositions with reduced surface staining

Disclosed herein are oral care compositions comprising a zinc amino acid halide complex, and linear polyvinylpyrrolidone and/or sodium tripolyphosphate, which compositions have improved rheological stability. Methods of making and using the compositions are also provided.

Oral care compositions comprising zinc amino acid halides

Disclosed are oral care compositions and the use of such oral care compositions for treating conditions caused by biofilm formation. Also disclosed are methods for inhibiting biofilm formation and/or degrading biofilm. The oral care composition includes a sesquiterpenoid and an antimicrobial agent, in which the sesquiterpenoid and the antimicrobial agent are present in an amount effective to inhibit and/or degrade a biofilm in the oral cavity.

Oral care composition

Growing community of inventors

Flemington, NJ, United States of America

Gregory Szewczyk