Seno Medical Instruments, Inc.

Gregory Schmid

Bryan Clingman

Jason Zalev

William Ackerman

Donald G Herzog

Remie J Smith

John Willick

An optoacoustic imaging system includes an ultrasound transducer array, first and second light sources and a switching power supply that generates power for the light sources. The switching power supply includes an input for impeding its switching operation. A data acquisition unit samples the ultrasound transducer array for a first predetermined period of time after a pulse of light from the first light source and for a second predetermined period of time after a pulse of light from the second light source and stores the sampled data. A master processor utilizes the input to impede operation of the switching operation of the switching power supply during the first predetermined period of time after a pulse of light from the first light source, and during the second predetermined period of time after a pulse of light from the second light source.

Noise suppression in an optoacoustic system

An optoacoustic system and method for providing enhanced laser safety includes a laser light source, a control and processing system, a laser override, and an array of optoacoustic transducers. The laser light source is capable of generating a laser light pulse upon receiving a laser light source trigger. The control and processing system is configured to generate a laser light source trigger, to receive and process ultrasound data, and to control operation of the optoacoustic system. The control and processing system determines whether received ultrasound data reflects acoustic coupling between the transducer array and the volume. The laser override is configured to automatically prevent the generation of a laser light pulse if received ultrasound data does not reflect acoustic coupling between the optoacoustic transducer array and the volume.

Optoacoustic imaging systems and methods with enhanced safety

A serialized probe component for an optoacoustic device has a unique identifier associated therewith and includes, in an embodiment, an operative connection between a read-write memory and the optoacoustic device. Software adapted to generate and store logs in a read-write memory is executed on the optoacoustic device and stores logs concerning utilization of the serialized probe component on the read-write memory. A method for logging operational information concerning an optoacoustic device is further disclosed.

Optoacoustic component utilization tracking

A method for controlling an optoacoustic imaging system includes the steps of analyzing sinogram data values to identify variations, storing information concerning the variations, generating first and second sinograms, and processing the sinograms to mitigate the effect of the variations. In the analyzing step, sinogram data values are analyzed to identify one or more variations that are related to performance of one or more of the discrete components of the optoacoustic imaging system. The identified variations are then stored. A first sinogram is generated by sampling transducer elements acoustically coupled with a surface of a volume for a predetermined period of time after delivery of a pulse of light having a first wavelength, the first sinogram containing one channel for each of the transducer elements. A second sinogram is generated by sampling the transducer elements acoustically coupled with the surface of the volume for the predetermined period of time after delivery of a pulse of light having a second wavelength, the second sinogram containing one channel for each of transducer elements. The first and second sinograms are processed using the stored information to mitigate the effect of the identified variations on the respective sinogram.

System and method for providing selective channel sensitivity in an optoacoustic imaging system

A system and method for adjusting the light output of an optoacoustic imaging system is presented. An optoacoustic imaging system includes a light source such as a laser, the light source having a light output control, a probe for delivering light to a volume, the probe being associated with one or more sensors, a light path operatively connected to the first light source, the light path providing light from the first light source to the probe. Generally, the light output of an optoacoustic imaging system may be harmful to the eye, and may be subject to maximum safe fluence levels incident upon the volume of interest in a clinical setting. Accordingly, the light output control may be set to an initial, relatively low value. After the light source is pulsed, the light output may be measured at or near the probe at the distal end of the light path. The measured light output can used to determine whether, and how much, to change the setting of the light output control. The system and method may also be used for closed loop control of the light output to keep fluence levels within a desired range. The rate of change of the light output control can be varied based upon the difference between the measured fluence and the desired fluence or range.

System and method for calibrating the light output of an optoacoustic probe

Systems and methods for relaying electrical signals representing acoustic response of a volume of tissue to light and ultrasound stimulation. In an embodiment, a plurality of ultrasound transducers receive acoustic energy from the volume and generate electrical energy, which is transmitted via an electrical path to a relay system. The ultrasound transducers are operated at a wide band frequency of at least 1 MHz to 5 MHz to receive acoustic energy from the volume of tissue responsive to light stimulation and at a narrower band frequency to receive acoustic energy from the volume of tissue responsive to acoustic stimulation. The relay system relays the electrical signals to an optoacoustic system or an ultrasound instrument for further processing depending on whether the electrical signals resulted from ultrasound or light stimulation. In an embodiment, optoacoustic, ultrasound, or other images are generated from the electrical signals and may be coregistered, overlayed, or displayed.

System and method for mixed modality acoustic sampling

System and method for adjusting the light output of an optoacoustic imaging system

A system and method are provided for normalizing range in an optoacoustic imaging system. In an embodiment, the system includes adjustable amplifiers and a probe having an array of transducer elements, each of the adjustable amplifiers being associated with one or more of the transducer elements. The transducer elements are acoustically coupled with a surface of a volume. The gain on the adjustable amplifiers is changed as a function of the passage of time during a predetermined period of time after a pulse of light. A sinogram is recorded by sampling the adjustably amplified plurality of transducer elements for the predetermined period of time. The sinogram is processed by substantially reversing the changing step mathematically, and storing the results in an expanded dynamic range sinogram. The expanded dynamic range sinogram provides sufficient numeric precision to permit the reversal of the changing step without materially decreasing the dynamic range of the information in the sinogram. An optoacoustic image is generated based upon the information contained in the expanded dynamic range sinogram.

System and method for normalizing range in an optoacoustic imaging system

A system and method for adjusting the light output of an optoacoustic imaging system. An optoacoustic imaging system includes a light source having a light output control, a probe for delivering light to a volume, the probe being associated with one or more sensors, a light path operatively connected to the first light source, the light path providing light from the first light source to the probe. To avoid unsafe fluence levels incident upon the volume of interest in a clinical setting, the light output control may be set to an initial, relatively low value. After the light source is pulsed, the light output may be measured at or near the probe at the distal end of the light path. The measured light output can used to determine whether, and how much, to change the setting of the light output control.

Growing community of inventors

San Antonio, TX, United States of America

Gregory Schmid