3M Innovative Properties Company

Solventum Intellectual Properties Company

Gregory M Jellum

Jerald K Rasmussen

Jonathan F Hester

Kannan Seshadri

Dean R Duffy

Clinton P Waller, Jr

Richard Allan Kirchner

Francis E Porbeni

Andrew W Vail

Donald E Young

Chris Manderfeld

John J Schmidt

Kenneth J Snider

Angelines A Castro Forero

Ali E Ozcam

John J Reese

Clinton P Waller

Described herein is a filtration media comprising: (i) a first filtration medium comprising an anion exchange nonwoven substrate, wherein the anion exchange nonwoven substrate comprises a plurality of quaternary ammonium groups; and (ii) a second filtration medium comprising a functionalized microporous membrane wherein the functionalized microporous membrane comprises a plurality of guanidyl groups; wherein the first filtration medium is positioned upstream of the second filtration medium.

Filtration medium sequence for biomaterial purification

A method of purifying a biological composition includes: disposing loose cationic ligand-functionalized staple fibers and a biological composition within a mixing volume of a vessel; agitating the biological composition and the loose cationic ligand-functionalized staple fibers while they are in intimate contact with each other within the mixing volume to provide modified fibers and a purified biological composition; and separating at least a portion of the purified biological composition from the modified fibers and any loose cationic ligand-functionalized staple fibers with which it is in contact. The loose cationic ligand-functionalized staple fibers have a modified surface layer comprising a grafted acrylic polymer comprising 10 to 100 percent by weight of a cationically-ionizable monomer unit. An article for purifying a biological composition includes: a vessel having a mixing volume disposed therein; and the loose cationic ligand-functionalized staple fibers disposed within the mixing volume.

Method of purifying a biological composition and article therefor

A filter frame assembly is disclosed comprising a perimeter member surrounding a fluid aperture adapted to accommodate a fluid flow from an upstream direction to a downstream direction, the perimeter member comprising a perimeter upstream surface, a perimeter downstream surface, and a perimeter outer surface connecting the perimeter upstream surface to the perimeter downstream surface. A gasket carrier is attached to the perimeter member and comprises a carrier outer portion facing generally away from the fluid aperture and a first outer portion sealing member projecting from the carrier outer portion.

Filter frame assembly with seal

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Marine on St. Croix, MN, United States of America

Gregory M Jellum