Id Biomedical Corporation of Quebec

Gregory Lee White

George H Lowell

David Hugh Jones

David S Burt

Kirkor Torossian

Louis F Fries, Iii

Martin Plante

Clement Rioux

An adjuvant complex composed of bacterial outer membrane protein proteosomes complexed to bacterial liposaccharide is prepared to contain the component parts under a variety of conditions. The complex can be formulated with antigenic material to form immunogenic compositions, vaccines and immunotherapeutics. An induced immune response includes protective antibodies and/or type 1 cytokines is shown for a variety of protocols.

Proteosome-liposaccharide vaccine adjuvant

Improved forms of vaccines which comprise proteosomes and protein antigens are described. Vaccines which contain influenza HA as the antigen are used for illustration as to demonstrate efficacy. Improvements in the preparation of the vaccines themselves and the proteosome component are also included.

Proteosome influenza vaccine

Growing community of inventors

Montreal, Canada

Gregory Lee White