Santen Sas

Novagali Pharma Sa

Institut National De La Sante Et De La Recherche Medicale

Targedys

Université´de Rouen

Centre Hospitalier Universitaire De Rouen

Other

Sofic (Ste Francaise D'instruments De Chirurgie)

Novagli Pharma S.a.

Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.

Gregory Lambert

Betty Philips

Laura Rabinovich-Guilatt

Frederic Lallemand

Pierre Dechelotte

Romain Legrand

Jonathan Breton

Serguei Fetissov

Jean-Sébastien Garrigue

Jean-Sebastien Garrigue

Nicolas Lucas

Séverine Bague

Laura Rabinovich-Guilatti

Naouel Tennoune

Simon Benita

Christophe Combes

Jürgen Wollbold

Cecile Arnaud

Pascal Candillon

Julien Lafosse

Laura Rabinovich

Emmanuelle De

Severine Bague

Philippe Chan-Tchi-Song

Sergueï Fetissov

Jerome Haas

Jurgen Wollbold

Compositions containing quaternary compounds in which the nitrogen atom is substituted by at least one alkyl group having at least 12 carbon atoms, and the composition includes at least 20% in weight by weight of the total composition, of ammonium halides in which the nitrogen atom is substituted by at least one alkyl group having at least 14 carbon atoms and more than 5%, preferably more than 7% in weight by weight of the total composition, of ammonium halides in which the nitrogen atom is substituted by at least one alkyl group having at least 16 carbon atoms. Also, ophthalmic oil-in-water emulsions containing such compositions, the ophthalmic emulsions being useful for eye care or for the treatment of eye conditions.

Oil-in-water emulsions comprising cetalkonium chloride and methods of making and using the same

The present invention relates to pharmaceutical and food compositions for inducing satiation and prolonging satiety in subjects in need thereof. In particular, the present invention relates to a method of inducing satiation in a subject in need thereof comprising administering to the subject an effective amount of a ClpB protein or an effective amount of a bacterium that expresses the ClpB protein.

Pharmaceutical and food compositions for inducing satiation and prolonging satiety in subjects in need thereof

The present invention relates to method of preventing, treating or attenuating obesity-related manifestations in a human or non-human mammal subject in need thereof, said method comprising orally administering to the subject a composition comprising an effective amountprobiotics; wherein said obesity-related parameters are selected from the group of hyperphagia, increased fat mass on lean mass ratio, increased waist circumference, postprandial hyperglycemia, fasting hyperglycemia and hypercholesterolemia.

Hafnia alvei impact on regulation of appetite and metabolic syndrome aspects

The present invention relates to pharmaceutical and food compositions for inducing satiation and prolonging satiety in subjects in need thereof. In particular, the present invention relates to a method of inducing satiation in a subject in need thereof comprising administering to the subject an effective amount of

based pharmaceutical and food compositions for inducing satiation and prolonging satiety

Methods for preparing oil-in-water emulsions comprising cetalkonium chloride

The present invention relates to ClpB expressing bacteria and their impact on obesity. The present invention relates to bacterial ClpB protein and ClpB expressing bacteria and their impact on eating disorders. The invention further relates to compositions comprising antibiotic directed against at least one ClpB expressing bacterium as well as probiotics not expressing ClpB protein and their use in the treatment or prevention of eating disorders. The invention also relates to diagnostic tools for determining whether a subject is likely to respond to a method of treating eating disorders and to methods of immunization against eating disorders.

Bacterial influence on regulation of appetite via ClpB protein mimicry of alpha-MSH

Emulsion compositions containing quaternary ammonium compounds

A protective sheath () for a cannula () arranged on a hub () which can be fitted onto a syringe (), the sheath including female elements intended to cooperate with male elements () of the hub () for guiding thereof, and characterized in that the female elements include a retracted position before use RBU, a retracted position during use RU, and a retracted position after use RAU, wherein the whole length of the cannula () is inside the sheath (), the female elements further include an ejection position E, wherein whole or part of the cannula () protrudes out of the sheath (), and further characterized in that at least two of the RBU, RU, and RAU positions are substantially transversally aligned.

Sheath protecting a cannula, and safety syringe comprising said sheath

The present invention relates to new processes for the preparation of oil-in-water emulsions useful in ophthalmic applications. In particular, processes are provided that include preparing a pre-concentrate of the oil-in-water emulsion, and diluting the pre-concentrate obtained to form the desired oil-in-water emulsion. The present invention also provides pharmaceutical compositions comprising an oil-in-water emulsion prepared by an inventive process, and methods of using these compositions for the treatment of an eye disease or condition.

Process for manufacturing ophthalmic oil-in-water emulsions

Emulsion compositions containing cetalkonium chloride

Described is the use of prodrug for the manufacture of a medicament useful for treating an ocular disease affecting the posterior segment of the eye, in a subject in need thereof, wherein the prodrug is a composition injected into the vitreous body, and the frequency of injections does not exceed one injection per month.

Method for treating eye disease or conditions affecting the posterior segment of the eye

Compositions containing quaternary ammonium compounds in which the nitrogen atom is substituted by at least one alkyl group having at least 12 carbon atoms, where composition includes at least 20% in weight by weight of the total composition, of ammonium halides in which the nitrogen atom is substituted by at least one alkyl group having at least 14 carbon atoms and more than 5%, preferably more than 7% in weight by weight of the total composition, of ammonium halides in which the nitrogen atom is substituted by at least one alkyl group having at least 16 carbon atoms. Ophthalmic oil-in-water emulsions containing such compositions, and the ophthalmic emulsions being are useful for eye care or for the treatment of eye conditions.

Compositions containing quaternary ammonium compounds

The present invention relates to a new therapeutic approach for the treatment of eye diseases or conditions that allows for the delivery of corticosteroids to the eye's surface but does not cause any of the usual side effects associated with topical administration of corticosteroids. More specifically, the present invention provides methods of treatment involving the administration of a corticosteroid prodrug, such as dexamethasone palmitate, to the surface of the eye. Also provided are pharmaceutical compositions and kits for carrying out such methods of treatment.

Topical methods and compositions for the treatment of eye diseases and conditions

Composition containing quaternary ammonium compounds in which the nitrogen atom is substituted by at least one alkyl group having at least 12 carbon atoms, the composition including at least 20% in weight by weight of the total composition, of ammonium halides in which the nitrogen atom is substituted by at least one alkyl group having at least 14 carbon atoms and more than 5%, preferably more than 7% in weight by weight of the total composition, of ammonium halides in which the nitrogen atom is substituted by at least one alkyl group having at least 16 carbon atoms. Ophthalmic oil-in-water emulsions containing such compositions, the ophthalmic emulsions being useful for eye care or for the treatment of eye conditions are also disclosed.

Growing community of inventors

Chatenay Malabry, France

Gregory Lambert