Molecular Devices Corporation

Other

Gregory L Kirk

Calvin Y Chow

Rick T Smethers

Vladimir J Drbal

Suresh N Mehta

Lev Leytes

Debra A Ross

John C Owicki

Jonathan Briggs

Michael M Lacy

Thomas L Smith

Briggs, Jonathan

Richard C Kuo

Timothy D Dawes

Albert K Harris

George Pontis

This invention encompasses a work station for conducting assays which comprises filtering assembly, a slide reading assembly, and a slide with a porous filter membrane wherein the slide has a means for aligning the slide within the filter assembly to filter reagents on predetermined portions of the porous filter membrane and also to position the slide in the slide reading assembly so that detection will occur in those same predetermined locations.

Analytical work station

One aspect of the invention is the method of operating a microphysiometer including a plunger assembly having a plunger body with a microchamber at one end for receiving a sample and a passage in the plunger body communicating with the microchamber comprises passing a medium transversely through the-sample in the microchamber. Another aspect of the invention is the construction of the plunger assembly wherein the sample is positioned in the microchamber and the passage and microchamber are constructed and arranged so that medium flow is transverse through the sample. The sample may be a tissue slice retained between a pair of screens or membranes, adherent cells on a mesh screen or non-adherent cells retained in a chamber defined by a washer and a pair of screens or membranes.

Transverse flow plungers for microphysiometers

This invention encompasses a slide reading assembly, and a slide with a porous filter membrane wherein the slide has a means for aligning the slide within a filter assembly to filter reagents on predetermined portions of the porous filter membrane and also to position the slide in a slide reading assembly so that detection will occur in those same predetermined locations.

Analytical slide with porous filter membrane

Growing community of inventors

Montgomery Township, NJ, United States of America

Gregory L Kirk