Evolved by Nature, Inc.

Allergan, Inc.

Silk Therapeutics, Inc.

Other

Tufts College

Tissue Regeneration, Inc.

Massachusetts Institute of Technology

Tufts University

Serica Technologies, Inc.

Gregory H Altman

Rebecca L Horan

Dylan S Haas

Enrico Mortarino

Rachel Lee Dow

Rachel M Lind

Rebecca L Lacouture

Jingsong Chen

David J Horan

Adam L Collette

Dennis E Van Epps

Wha Bin Im

Guang-Liang Jiang

Sara Ann Johnson

Jingson Chen

Maria L Ufret

Markrete Krikorian

Carlos J Bosques

Kevin T Healy

David L Kaplan

Wha-Bin Im

Peng Xu

Gordana Vunjak-Novakovic

Ivan Martin

Erlei Jin

Patrick Yacono

Patrik Johansson

Jing Song Chen

Rebeca L Horan

David Horan

In an embodiment, a moisturizing composition includes a silk solution, wherein the silk solution comprises about 1% to about 10% (w/v) of pure silk fibroin-based protein fragments that are substantially devoid of sericin; hyaluronic acid; an oil or butter; and a pH adjusting agent.

Silk-based moisturizer compositions and methods thereof

Silk infused performance apparel and methods of preparing the same are disclosed herein. In some embodiments, silk performance apparel includes textiles, fabrics, consumer products, leather, and other materials that are coated with aqueous solutions of pure silk fibroin based protein fragments. In some embodiments, coated apparel products, textiles, and upholstery, as well as other materials, exhibit surprisingly improved moisture management properties, resistance to microbial growth, increased abrasion resistance, and flame resistance.

Silk performance apparel and products and methods of preparing the same

Silk performance apparel and methods of preparing the same are disclosed herein. In some embodiments, silk performance apparel includes textiles, fabrics, consumer products, and other materials that are coated with aqueous solutions of pure silk fibroin-based protein fragments. In some embodiments, coated apparel products exhibit surprisingly improved moisture management properties and increased resistance to microbial growth.

Silk coated and/or infused performance materials, apparel, and methods of preparing the same are disclosed herein. In some embodiments, silk performance apparel includes textiles, fabrics, consumer products, and other materials that are coated with aqueous solutions of pure silk fibroin-based protein fragments having low, medium, and/or high molecular weight in various ratios.

Silk coated fabrics and products and methods of preparing the same

Hyaluronic acid and silk fibroin or silk fibroin fragments tissue fillers and methods of making and using the same are provided herein. In some embodiments, the disclosure relates to a biocompatible tissue filler comprising silk fibroin or silk fibroin fragments, hyaluronic acid (HA), and polyethylene glycol (PEG) and/or polypropylene glycol (PPG), wherein a portion of the HA is modified or crosslinked by one or more linker moieties comprising one or more of polyethylene glycol (PEG), polypropylene glycol (PPG), and a secondary alcohol, wherein the linker moieties are attached to the HA at one end of the linker.

Silk-hyaluronic acid tissue fillers and methods of making and using the same

Silk processed, coated, repaired, and/or infused faux or bonded leather, or faux or bonded leather articles, and methods of preparing the same are disclosed herein.

Silk protein bonded layered materials and methods of making and using thereof

A composition is disclosed that includes pure silk fibroin-based protein fragments that are substantially devoid of sericin, wherein the composition has an average weight average molecular weight ranging from about 17 kDa to about 38 kDa, wherein the composition has a polydispersity of between about 1.5 and about 3.0, wherein the composition is substantially homogeneous, wherein the composition between 0 ppm to about 500 ppm of inorganic residuals, and wherein the composition includes between 0 ppm to about 500 ppm of organic residuals.

Stable silk protein fragment compositions

Hyaluronic acid and silk protein fragments based tissue fillers and methods of using the same are provided herein.

Silk-hyaluronic acid based tissue fillers and methods of using the same

Silk infused performance apparel and methods of preparing the same are disclosed herein. In some embodiments, silk performance apparel includes textiles, fabrics, consumer products, leather, and other materials that are coated with aqueous solutions of pure silk fibroin-based protein fragments. In some embodiments, coated apparel products, textiles, and upholstery, as well as other materials, exhibit surprisingly improved moisture management properties, resistance to microbial growth, increased abrasion resistance, and flame resistance.

Growing community of inventors

Arlington, MA, United States of America

Gregory H Altman