Iowa State University Research Foundation Inc

Pathogenesis Corporation

Gregory G Mahairas

Charles K Stover

F Chris Minion

Sreekumar A Menon

The invention features fusion agents such as fusion proteins that are useful for the treatment of and prevention from diseases that are susceptible to the effects of cellular (Th1 type) immune responses. Also encompassed by the invention are nucleic acids encoding the fusion proteins of the invention, vectors containing the nucleic acids, and cells containing the vectors. The invention includes methods of making and using the fusion agents of the invention.

Vaccine adjuvant

The present invention provides specific genetic deletions that result in an avirulent phenotype of a mycobacterium. These deletions may be used as phenotypic markers of providing a means for distinguishing between disease-producing and non-disease producing mycobacteria.

Growing community of inventors

Seattle, WA, United States of America

Gregory G Mahairas