Johns Hopkins University

Sanaria Inc.

Gregory Chirikjian

Russell H Taylor

David Stein

Nabil Simaan

Paul W Flint

Stephen L Hoffman

Iulian Ioan Iordachita

Sumana Chakravarty

Joshua D Davis

Paul J Biermann

Robert J Webster, Iii

Allison Mariko Okamura

Kenneth Y Goldberg

Balazs Peter Vagvolgyi

Jin Seob Kim

Noah Cowan

Ron Alterovitz

Can Kocabalkanli

Ryan J Forrest

Paul Flint

Michael D M Kutzer

Amanda Canezin

Robert Matteson

Henry Phalen

Mariah Schrum

Hongtao Wu

Mengdi Xu

Michelle Laskowski

Shengnan Lu

Michael Aaron Pozin

Brian K Chirikjian

Ting Da

John S Chirikjian

Systems and methods for providing a combined mosquito staging and dissection system are disclosed. The system can include a mosquito staging subsystem; a robotic pick-and-place station; and a dissection, extrusion, collection, and disposal subsystem. The subsystems can include one or more stations to provide orientation, decapitation, extrusion of salivary glands, and disposal of carcasses of the mosquitoes. The resident live sporozoites from the salivary glands can be used to produceSPZ-based vaccines.

Apparatus and method of use for an automated mosquito salivary gland extraction device

Systems and methods for conformal additive manufacturing are disclosed. In particular, systems and methods are disclosed utilizing variable offset curves and/or a manipulated solution to Laplace's equation to generate layers between an initial boundary and a desired boundary.

Systems and methods for conformal additive manufacturing

A device and method of use for augmenting the extraction of salivary glands from-infected mosquitoes, where the sporozoite stage ofprimarily resides. Sporozoites are useful for research as well as for the immunogen in whole parasite vaccines for the prevention of malaria. The device and methods of use disclosed herein greatly increase the rate at which sporozoites can be harvested.

Mosquito salivary gland extraction device and methods of use

Featured are systems, devices and apparatuses for use in minimally invasive surgical, diagnostic or therapeutic methods and/or techniques, in particular methods and/or techniques for a mammalian throat. In particular embodiments, a dexterity apparatus including one or more dexterity devices is featured, where each of the dexterity devices comprises surgical tools and each is configured and arranged with end-tip dexterity for enhanced manipulation. A portion of the dexterity devices is snake like, which is re-configurable (i.e., can be bent) so as to in effect maneuver the surgical tool and put the tool in a desired position with respect to the surgical site. Another portion of the dexterity device includes the surgical tool thereby providing the capability of performing surgical actions such as sewing, gripping, soft tissue manipulation, cutting and suction of saliva, blood and other materials from the surgical site.

Devices, systems and methods for minimally invasive surgery of the throat and other portions of mammalian body

Disclosed is a system for percutaneously steering a surgical needle. Needle steering is accomplished by taking advantage of a deflection force imparted on the bevel tip of the needle by the tissue medium as the needle is pushed through the tissue. By controlling the translation speed and rotation angle of the bevel, a flexible needle may be steered substantially without deflecting or distorting the tissue. The control inputs (translation speed and rotation angle) are computed based on a 'bicycle' non-holonomic kinematic model that is a function of mechanical properties of the tissue medium. The system may be used with image-based feedback, which may provide for feedback-based refinement of the model as the needle propagates through the tissue.

Distal bevel-tip needle control device and algorithm

Growing community of inventors

Towson, MD, United States of America

Gregory Chirikjian