Novartis Ag

Harland Medical Systems, Inc.

Pursuit Vascular, Inc.

Gregory Carlson

Michael Hugh Quinn

Barry L Atkins

Paul J Buscemi

Robert J Ziebol

Robert G Walsh

William S Nettekoven

Peter Wachtel

Joshua Andrew Wallach

Edgar Allan Blair

Robert H Weinmann

The present invention relates to coatings for devices such as medical devices that are useful for coating a variety of different types of material surfaces, including polymer and metal surfaces. The present invention also includes the method of using the coated device and methods to make the coated device and coating.

Coating composition comprised of a hydrophilic crosslinker, a hydrophobic crosslinker and optionally a hydrogel and methods of making and using the same

The present invention provides an ink and a method of using the ink for making colored contact lenses. The ink comprises at least one colorant, a silicone-containing binder polymer, a solvent, a vinylic-monomer mixture, and optionally a photoinitiator or thermal initiator. The silicone-containing binder polymer is a copolymerization product of a polymerizable mixture including (i) at least one hydrophilic vinylic monomer; (ii) at least one functionalizing vinylic monomer containing at least one functional group selected from the group consisting of hydroxyl group &#x2014;OH, amino group &#x2014;NHR (wherein R is hydrogen or C1 to C8 alkyl), carboxylic group &#x2014;COOH, epoxy group, amide group &#x2014;CONHR, and combinations thereof; (iii) at least one silicone-containing vinylic monomer or macromere.

Colored ink for pad transfer printing of silicone hydrogel lenses

A system for delivering an antimicrobial agent into the lumen of a trans-dermal catheter. In an embodiment, the system comprises an elongate member configured for insertion into a lumen of a catheter; an expandable portion of the elongate member, said expandable portion configured to increase in diameter upon exposure to an aqueous fluid; and an antimicrobial composition positioned to be delivered into the catheter. In another embodiment, the system comprises an elongate member configured for insertion into a lumen of a trans-dermal catheter, said elongate member comprising a hydrogel; and an antimicrobial composition positioned to be delivered into the catheter; wherein the elongate member defines a volume of liquid that is at least substantially contained within the lumen of the trans-dermal catheter.

Device for delivery of antimicrobial agent into trans-dermal catheter

The present invention provides a method for making colored silicone hydrogel contact lenses. The method of the invention comprises the steps of: (a) providing a contact lens constructed of a silicone hydrogel; (b) applying a color coat to at least a portion of a surface of the lens with an ink, wherein the ink comprises at least one colorant, a silicone-containing binder polymer, one or more vinylic monomers, and optionally a diluent, wherein the silicone-containing binder polymer is a copolymerization product of a polymerizable mixture including (i) at least one hydrophilic vinylic monomer; (ii) at least one functionalizing vinylic monomer; (iii) at least one silicone-containing vinylic monomer or macromer; (c) curing the ink in the presence of an adhesion promoter, thereby causing the color coat to adhere to the lens.

The present invention provides a method for making colored silicone hydrogel contact lenses. The method of the invention comprises the steps of: (a) applying a color coat to at least a portion of at least one of molding surfaces of a lens mold with an ink, wherein the ink comprises at least one colorant, a binder polymer, an adhesion promoter, and optionally a diluent, wherein the binder polymer is a copolymerization product of a polymerizable mixture including (i) at least one hydrophilic vinylic monomer; (ii) at least one functionalizing vinylic monomer containing at least one functional group selected from the group consisting of hydroxyl group &#x2014;OH, amino group &#x2014;NHR (wherein R is hydrogen or Cto Calkyl), carboxylic group &#x2014;COOH, epoxy group, amide group &#x2014;CONHR, and combinations thereof; (iii) at least one silicone-containing vinylic monomer or macromer, and (iv) optionally one or more components selected from the group consisting of a polymerization initiator, a chain transfer agent, and a solvent, wherein the mold has a lens-forming cavity between the molding surfaces, wherein the colored coat contains a first surface exposed to the interior of the lens-forming cavity and a second surface in contact with the molding surface; (b) curing the ink printed on the mold; (c) dispensing a silicone hydrogel lens-forming material into the lens-forming cavity of the mold; (d) curing the lens-forming material within the lens-forming cavity to form the contact lens, whereby the colored coat detaches from the molding surface and becomes integral with the body of the contact lens.

Pad transfer printing of silicone hydrogel lenses using colored ink

A prepolymer is prepared by reacting a mixture containing (a) at least one multifunctional compound, (b) at least one diisocyanate, and (c) at least one diol. The diol has a weight average molecular weight of at most 6000. The prepolymer, when reacted with an excess of water, forms a hydrogel polymer. The mixture of the prepolymer and water may be reaction molded, and used to form a contact lens.

Growing community of inventors

Bloomington, MN, United States of America

Gregory Carlson