Massachusetts Institute of Technology

Tufts College

Swinburne Uiniversity of Technolooy

Dow Corning Corporation

Gregory C Rutledge

Trevor Alan Hatton

Sergey Fridrikh

David L Kaplan

Minglin Ma

Bernhardt Levy Trout

Hyoung-Joon Jin

Keith M Forward

Alexander H Slocum, Jr

Won Sik Kim

Karen K Gleason

Paula T Hammond

Lev E Bromberg

Kevin C Krogman

Allan Stuart Myerson

Yi Du

Jung-Hoon Chun

Xianwen Mao

Salvatore Mascia

Nikhil Padhye

Yinying Ren

Malancha Gupta

Emily Chang

Himanshu Hemant Dhamankar

Blair Kathryn Brettmann

Peter Kingshott

Jung Ah Lee

Mao Wang

Liang Chen

David Nielsen

Randal M Hill

Joseph L Lowery

Randall M Hill

Karl Pavey

Yu Mao

Yen Truong

Jay Hoon Park

Maryanne Spiers

Nicholas M Sondej

Indrani Bhattacharyya

James M B Evans

Wenda Tian

Daniel Eldridge

Ryan Richard Slaughter

James Mb Evans

Aspects described herein relate generally to adsorbent systems and methods for capturing and/or separating organic species (e.g., uncharged organic species) from mixtures with water.

Adsorbents, systems, and methods for separation of organic species from water

A method of forming an acid-doped polyaniline (emeraldine salt) (PANi-ES) solution including steps of: (i) mixing polyaniline (emeraldine base) (PANi-EB) with a PANi-EB solvent and a gel-inhibitor to form a gel-inhibited PANi-EB solution; (ii) removing the gel-inhibitor from the gel-inhibited PANi-EB solution to form a PANi-EB solution; and (iii) adding an acid dopant to the PANi-EB solution to form a PANi-ES solution.

Process of forming an acid-doped pol y aniline solution

Disclosed are methods of forming a plurality of fibers, and nanofibers produced from such a method.

Gel-electrospinning process for preparing high-performance polymer nanofibers

Methods and systems for manufacturing a tablet are generally provided. Certain embodiments comprise electrodepositing (e.g., electrospinning) a material (e.g., the tablet material, for example, within a fluid) onto a substrate. The substrate can be, for example, an elongated rod. In some such embodiments, after material has been electrodeposited onto the substrate, a die comprising a cavity and the substrate can be moved relative to each other such that the electrodeposited material is at least partially stripped from the substrate and/or at least partially deposited into the cavity of the die. Some embodiments comprise compressing the material in the cavity to form a tablet.

Methods and systems for manufacturing a tablet

Disclosed are methods that utilize the differences in physical properties between two coating fluids to form core-shell particles or core-shell fibers by coaxial free-surface electrospinning. The methods are able to achieve higher productivity than known methods, and are tunable. Nonwoven fiber mats of electrospun fibers have garnered much scientific and commercial interest in recent years due to their unique properties, such as their high porosity, high surface area and small diameter fibers.

Formation of core-shell fibers and particles by free surface electrospinning

Layer processing for pharmaceuticals, and related systems, methods, and articles are generally described. In some embodiments, ingestible pharmaceutical products (e.g., tablets) can be formed by processing one or more layers containing a pharmaceutically active composition. For example, at least one layer containing a pharmaceutically active composition can be manipulated (e.g., folded, rolled, stacked, etc.) such that the average thickness of the product formed by the manipulation is at least about two times the average thickness of the portions of the layer(s) used to form the product. In some embodiments, after the layer is manipulated, it can be processed (e.g., cut, coated, etc.) to form a final product such as, for example, a tablet.

Layer processing for pharmaceuticals

One aspect of the invention relates to a method of preparing metal oxide coated substrates for various potential applications, and the coated substrate formed thereby.

Highly reactive multilayer assembled coating of metal oxides on organic and inorganic substrates

Described is the application of layer-by-layer (LbL) electrostatic assembly techniques to electrospun nanofibers in order to fabricate novel, breathable electrospun fiber-based chemical and biological detoxifying protective fabrics and filters. The combination of layer-by-layer electrostatic assembly and electrospinning technique allows one to take advantage of high specific surface area, light weight and breathability of electrospun fiber mats while simultaneously providing the versatility to incorporate different functional polyelectrolytes to achieve multifunctional coatings for both chemical and biological protection together. The functionalized fiber mats can be incorporated into breathable chemical and biological protective fabrics, filters and masks. In addition, LbL electrostatic coating of porous non-woven materials provides the versatility to generate multifunctional polymer-based membrane materials for other applications.

Multifunctional electroprocessed membranes

The present invention relates to fibers exhibiting a water contact angle of above 150&#xb0; and water contact angle hysteresis of below 15&#xb0;, methods of producing the same, and applications thereof. The present invention further relates to superhydrophobic fiber mats, methods of producing the same, and applications thereof.

Superhydrophobic fibers and methods of preparation and use thereof

The present invention provides an all-aqueous process and composition for production of silk biomaterials, e.g., fibers, films, foams and mats. In the process, at least one biocompatible polymer, such as poly(ethylene oxide) (PEO) (a well-documented biocompatible material), was blended with the silk protein prior to processing e.g., electrospinning. We discovered that this step avoids problems associated with conformational transitions of fibroin during solubilization and reprocessing from aqueous solution which lead to embrittled materials. Moreover, the process avoids the use of organic solvents that can pose problems when the processed biomaterials are exposed to cells in vitro or in vivo.

Silk biomaterials and methods of use thereof

Disclosed is a versatile method to produce superhydrophobic surfaces by combining electrospinning and initiated chemical vapor deposition (iCVD). A wide variety of surfaces, including electrospun polyester fibers, may be coated by the inventive method. In one embodiment, poly(caprolactone) (PCL) was electrospun and then coated by iCVD with a thin layer of hydrophobic polymerized perfluoroalkyl ethyl methacrylate (PPFEMA). In certain embodiments said coated surfaces exhibit water contact angles of above 150 degrees, oleophobicities of at least Grade-8 and sliding angles of less than 12 degrees (for a water droplet of about 20 mg).

Superhydrophobic fibers produced by electrospinning and chemical vapor deposition

Growing community of inventors

Newton, MA, United States of America

Gregory C Rutledge