Integenx, Inc.

Gregory Bogdan

Stevan Bogdan Jovanovich

William D Nielsen

David Eberhart

Ezra Van Gelder

Michael Recknor

Omar EL-Sissi

Richard Joseph Belcinski

David W Wyrick

David Wyrick

This disclosure provides an integrated and automated sample-to-answer system that, starting from a sample comprising biological material, generates a genetic profile in less than two hours. In certain embodiments, the biological material is DNA and the genetic profile involves determining alleles at one or a plurality of loci (e.g., genetic loci) of a subject, for example, an STR (short tandem repeat) profile, for example as used in the CODIS system. The system can perform several operations, including (a) extraction and isolation of nucleic acid; (b) amplification of nucleotide sequences at selected loci (e.g., genetic loci); and (c) detection and analysis of amplification product. These operations can be carried out in a system that comprises several integrated modules, including an analyte preparation module; a detection and analysis module and a control module.

Sample preparation, processing and analysis systems

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San Jose, CA, United States of America

Gregory Bogdan