The Dow Chemical Company

Gregory A Bradfisch

Susan Wollowitz

Sudarshan K Malhotra

James E Dripps

Ingrid L Knox

Substituted N-cyanomethyl-2-pyridinones were prepared by the reaction of alkali metal substituted-2-pyridinates with monohaloacetonitriles and found to possess insecticidal properties. The alkali metal substituted-2-pyridinates can be preformed or prepared from the corresponding 2-halopyridines or 2-pyridinols in the reaction medium. N-cyanomethyl-3-fluoro-5-(trifluoromethyl)-2-pyridinone, for example, was prepared from 2,3-difluoro-5-(trifluoromethyl)pyridine and found to control aster leafhoppers both on contact and systemically.

Growing community of inventors

Concord, CA, United States of America

Gregory A Bradfisch