Abbott Molecular Inc.

Gregor W Leckie

Ning Tang

Vihanga Pahalawatta

Andrea Frank

Hong Wang

John Lampinen

Klara Abravaya

Joshua Kostera

Reuben J Ofsaiof

Roy M Vijesurier

Provided herein are compositions and methods useful for the detection of MTB. In particular, provided herein are kits, reagents, reaction mixtures, and methods involving such for nucleic acid amplification and detection procedures, which specifically and sensitively detect MTB in samples.

Compositions and methods for the detection and analysis of

Provided herein are compositions and methods for diagnosing and characterizing tuberculosis infection. In particular, provided herein are compositions and methods for identifying drug resistant tuberculosis.

Compositions and methods for identifying drug resistant tuberculosis

The present invention provides methods, kits, and oligonucleotides for detecting and analyzing the nucleotide sequence of a reverse transcriptase (RT) region of the polymerase (Pol) gene of Hepatitis B Virus (HBV). In certain embodiments, a target RT region is amplified and subjected to DNA sequencing. The sequence obtained is compared to one or more DNA sequences characteristic of an HBV genotype or serotype, and/or one or more DNA sequences characteristic of an HBV mutation that confers resistance to a drug or vaccine, to determine the HBV genotype or serotype of the amplified product and/or the presence or absence of one or more DNA sequences characteristic of an HBV mutation that confers resistance to a drug or vaccine.

Hepatitis B virus typing and resistance assay

Compositions and methods for the detection and analysis of mycobacterium tuberculosis

Growing community of inventors

Des Plaines, IL, United States of America

Gregor W Leckie