Toshiba Medical Systems Corporation

Alpheus Medical, Inc.

Kabushiki Kaisha Toshiba

Gregg Miller

Braden Eliason

Vijay Agarwal

Jeremy Ling

John Ballard

Ultrasound transducer element arrays using acoustic ensonification drive patterns via a patient interface for sonosensitizer activation in sonodynamic therapy. Incoherent acoustic field generation varying phase, frequencies, and/or amplitude via controlled delivery of low intensity planar acoustic waves. Method includes generating a first and a second signal to generate respective acoustic ensonification drive patterns with phase, frequency, and amplitude and generating at least one relative phase, frequency or amplitude difference to generate a third incoherent acoustic ensonification pattern to activate a sonosensitizer. Calibration and complementary therapy procedures to improve cell susceptibility of cells to sonodynamic therapy are disclosed.

Ultrasound arrays for enhanced sonodynamic therapy for treating cancer

Incoherent field sonodynamic therapy for treating cancer

In general, embodiments of the ultrasound imaging system save power in relation to a predetermined active aperture and or a predetermined update depth. With respect to a predetermined active aperture, the imaging system saves power by reducing or turning off a predetermined portion of the receive electronics when the predetermined receive electronics portion is not operating in relation to the active aperture range. That is, in a first power saving mode, the predetermined receive electronics portion operates only when it is collecting and or processing the data inside the active aperture range. Furthermore, with respect to a predetermined update depth, the imaging system saves power by reducing the operational frequency as the predetermined receive electronics portion collects or process the data from a deeper area. That is, in a second power saving mode, the predetermined receive electronics portion operates less frequently when it is collecting and or processing the data from the middle or far range than the near range. Lastly, the imaging system saves power by modifying the operation as the predetermined receive electronics portion collects or process the data depending upon the active aperture and or the update depth. That is, in a third power saving mode, the predetermined receive electronics portion operates at least less frequently when it is collecting and or processing the data from the outside the active aperture and or at a far update depth. In other words, the third power saving mode is a hybrid or combination of the first and second power saving modes.

Variable power saving processing scheme for ultrasound beamformer functionality

An ultrasound device including a main processing unit, a probe part, an array, and an apodization unit that receives an ultrasound signal from the array, the signal having multiple channels, that determines a weight for each channel based on an apodization profile being one of ring-centered and edge-centered, and that multiplies the received ultrasound signal by the determined weight for each channel. The array includes a first area including a first plurality of elements having a first functionality, a second area including a second plurality of elements having a second functionality, and a third area including a third plurality of elements having a third functionality different from the first functionality. The second area further includes a fourth area having a number of elements that are switchable between the second and third types of functionality. The array also includes a dynamic spot including the third and fourth areas.

Medical ultrasound 2-D transducer array architecture: spot of arago

Growing community of inventors

Boulder, CO, United States of America

Gregg Miller