Valentx, Inc.

Greg Fluet

Mitchell Dann

James Wright

Gerard Von Hoffmann

Joshua Butters

Jonathan Kagan

Lee Guterman

Paul Swain

Cole Chen

Christopher Paul Swain

John C Hancock

Josiah E Verkaik

Bobby Griffin

The present invention provides devices and methods for attachment of an endolumenal gastrointestinal device, such as an artificial stoma device, a gastrointestinal bypass sleeve or other therapeutic or diagnostic device, within a patient's digestive tract. In one application of the invention, an endolumenal bypass sleeve is removably attached in the vicinity of the gastroesophageal junction to treat obesity and/or its comorbidities, such as diabetes. The bypass sleeve may be at least partially deployed by eversion.

Devices and methods for endolumenal gastrointestinal bypass

Disclosed herein are elongate flexible medical devices which are capable of axial elongation through a mechanism of eversion or toposcopic expansion. In general, this may be accomplished by providing a flexible tubular body having a proximal end and a distal end. Retraction of the distal end in a proximal direction through the tubular body inverts the tubular body upon itself, causing an axial shortening of an overall length of the tubular device. An original length of the tubular device can be restored by coupling a pressurized media to the proximal end of the tubular device. If the distal end of the tubular device is temporarily restricted or closed, the pressurized media causes the distal end of the tubular device to travel distally until a full length of the tubular device has been restored.

Methods for toposcopic sleeve delivery

Disclosed herein are systems and methods for attaching or maintaining the position of a therapeutic or diagnostic device in a body lumen, such as the GI tract without necessarily requiring any penetrating attachments through any body walls. The system can include at least two elements: a proximal orientation element and a distal support element. The proximal orientation element can be configured to reside at least partially within the esophageal lumen and the distal support element can be configured to reside in the stomach, such as along the greater curve of the stomach. An intragastric support system can have a first configuration in which the long axis of the proximal orientation element is substantially parallel and/or substantially coaxial with the long axis of the distal support element, and a second configuration in which the long axis of the proximal orientation element is not substantially coaxial with the long axis of the distal support element. The second configuration can thus advantageously retain the intragastric support system in place and prevent unwanted proximal migration of the distal support element into the esophagus or distal migration into the intestine.

Methods and devices for intragastric support of functional or prosthetic gastrointestinal devices

Disclosed herein are elongate flexible medical devices which are capable of axial elongation through the mechanism of eversion or toposcopic expansion. In general, this may be accomplished by providing a flexible tubular device having a proximal end and a distal end. Retraction of the distal end in a proximal direction through the tubular body inverts the tube upon itself, causing an axial shortening of the overall length of the device. The original length of the device can be restored by coupling a pressurized media to the proximal end of the sleeve. If the distal end of the sleeve is temporarily restricted or closed, the pressurized media causes the distal end of the sleeve to travel distally until the full length of the sleeve has been restored.

Toposcopic access and delivery devices

Methods and devices for gastrointestinal stimulation are disclosed. In one embodiment, disclosed is an electrical stimulator device that includes a circuit board and a battery contained within a base housing; a conduction element; and at least one electrode. In some embodiments, the stimulator base housing can be directly attached to a wall of a body lumen. In other embodiments, the stimulator base housing can be attached to a cuff or a sleeve device. In still other embodiments, one or more elements of the system are free-floating within the GI tract. The devices can be delivered endoscopically, and in some embodiments toposcopically.

Growing community of inventors

Jackson, WY, United States of America

Greg Fluet