Zoetis Services LLC

Zoetis LLC

Celgene Corporation

Ah USA 42 LLC

Graham M Kyne

Richard Andrew Ewin

Paul D Johnson

Rajendran Vairagoundar

Michael P Curtis

Matthew W Bedore

Tomasz Respondek

Sanjay Menon

Susan M K Sheehan

Todd M Maddux

John Adam Wendt

Kevin Ronald Condroski

Valerie Ann Vaillancourt

Timothy L Stuk

Natalie Anne Hawryluk

Timothy Allan Johnson

Stacie S Canan

Donald James Skalitzky

Brian A Duclos

Mark R Cox

Tom L McTier

Susan Mary Kult Sheehan

Susan M Sheehan

Christopher Scott Knauer

Michael Curtis

Govindan Subramanian

Edmund Lee Ellsworth

Nathan Anthony Logan Chubb

Derek James Sheehan

Jinxia (Nancy) Deng

Jinxia Deng

William Howson

Christoper S Knauer

Tim A Johnson

Nathan A L Chubb

Sanjay Rajagopal Menon

Michael Paul Curtis

Todd Maddux

Richard A Ewin

Andrea K Haber-Stuk

Richard M Goodwin

Christopher S Knauer

Tom L Mctier

Denis Billen

Susan Mary Sheehan

Nathan A Chubb

Provided herein are Heterocyclic compounds of formula I:

Heterocyclic compounds and their use for treatment of helminthic infections and diseases

Defined herein are immunomodulating Formula (1) compounds wherein R, R, R, R,

Immunomodulating urea azalides

The present invention provides cyclic depsipeptides of Formula (1), stereoisomers thereof, and veterinary acceptable salts thereof wherein each of R, R, R, R, L, and L, are as defined herein. The present invention also contemplates compositions and methods of treatment as an endoparasiticide with a Formula (1) compound.

Endoparasitic depsipeptides

The present invention provides cyclic depsipeptides of Formula (1), stereoisomers thereof, and veterinary acceptable salts thereof wherein each of R, R, R, R, L, and Lare as defined herein. The present invention also contemplates compositions, methods of treatment, and uses as a medicament to treat an animal for an endoparasitic infection with a Formula (1) compound.

Defined herein are immunomodulating Formula (1) compounds wherein R, R, R, R, Rand W are as defined herein, stereoisomers thereof, and pharmaceutically acceptable salts thereof; and compositions comprising said compounds. The invention also includes methods for treating an inflammatory and/or immunological disease or disorder in an animal by administering a therapeutically effective amount of a Formula (1) compound, stereoisomer thereof, and a pharmaceutically acceptable salt thereof; or use of said compound of Formula (1) to prepare a medicament for treating an inflammatory and/or immunological disease or disorder in an animal.

Provided herein are Heterocyclic compounds of formula I: 

The present invention provides Formula (1) compounds that are gamma-carbolines, Formula (1) wherein R1, R1, R1, R1, R2, R3, and '-' are as defined herein; veterinary acceptable salts thereof, and stereoisomers thereof, which act as parasiticides, in particular, endoparasiticides.

Carboline antiparasitics

The present invention provides novel phenicol derivatives, their use for the treatment of infections in mammals, pharmaceutical compositions containing these novel compounds, and methods for the preparation of these compounds.

Phenicol antibacterials

This invention recites isoxazoline substituted derivatives of Formula (1) stereoisomers thereof, geometric isomers thereof, veterinarily acceptable salts 5 thereof, compositions thereof, and their use as a parasiticide in animals. The variables A, W, R 1a, R 1b, R 1c, R 2, R 3, R 5, and n are as described herein. 

Isoxazoline derivatives as antiparasitic agents

The present invention provides novel cephalosporin derivatives of formula I, 

Cephalosporins useful as antibacterial agents

This invention recites isoxazoline substituted azetidine derivatives of Formula (1) stereoisomers thereof, veterinarily acceptable salts thereof, compositions thereof, and their use as a parasiticide in mammals and birds. R, R, R, R, R, R, R, and n are as described herein.

Growing community of inventors

Portage, MI, United States of America

Graham M Kyne