Abbott Laboratories Corporation

Medisense, Inc.

Graham J Hughes

Jared L Watkin

Geoffrey Roger Chambers

Gary F Prokop

Eric B Shain

Timothy P Henning

Andrew J Muetterties

Douglas F Young

Thomas G Schapira

David Dean Cunningham

Joshua P Goldfarb

Gurdial Singh Sanghera

Simon William Bayliff

Nigel F Carter

Geoffrey R Chambers

Steven Scott

Method and apparatus for obtaining a sample of blood from a patient for subsequent diagnostic tests, e.g., glucose monitoring. In one aspect of the invention, the method comprises the steps of: In another aspect of the invention, an apparatus for carrying out the method described previously is provided. The apparatus comprises:

Method and apparatus for obtaining blood for diagnostic tests

An electrochemical sensor electrode strip that measures analyte concentration in an aqueous sample as small as 2.5 to 2.0 .mu.L is described. Reduction in the minimum sample size is achieved by means of a dielectric coating impregnated into peripheral regions of one or more hydrophilic mesh layers, thereby reducing sample dead volume. The mesh layers are located between an electrode support and a cover layer, which cover layer includes an aperture located upstream from an electrode arrangement.

Low volume electrochemical sensor

Method and apparatus for obtaining a sample of blood from a patient for subsequent diagnostic tests, e.g., glucose monitoring. In one aspect of the invention, the method comprises the steps of:

An electrode strip for use in an electrochemical sensor for measuring a compound in a sample is provided, including an electrode support, a reference or counter electrode disposed on the support, a working electrode spaced from the reference or counter electrode on the support, a covering layer defining an enclosed space over the reference and working electrodes and having an aperture for receiving a sample into the enclosed space, and a plurality of mesh layers interposed in the enclosed space between the covering layer and the support, the covering layer having a sample application aperture spaced from said electrodes and said reference electrode spaced from said working electrode at a position remote from and on the opposite side of said working electrode from said aperture. The working electrode includes an enzyme capable of catalyzing a reaction involving a substrate for the enzyme or a substrate catalytically reactive with an enzyme and a mediator capable of transferring electrons transferred between the enzyme-catalyzed reaction and the working electrode to create a current representative of the activity of the enzyme and representative of the compound.

Electrochemical sensor

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Oxford, United Kingdom

Graham J Hughes