Commonwealth Scientific and Industrial Research Organisation

Clinical Genomics Pty. Ltd.

Graeme P Young

Trevor John Lockett

Peter Laurence Molloy

Susanne Kartin Pedersen

Lawrence Charles Lapointe

Robert Dunne

Glenn Southwell Brown

Lloyd Douglas Graham

William J Wilson

Lawrence Clarence Lapointe

Disclosed are nucleic acid, RNA, and protein expression profiles which are indicative of the onset, predisposition to the onset and/or progression of a large intestine neoplasm. More particularly disclosed are nucleic acid molecules, the expression profiles of which are indicative of the onset and/or progression of a colorectal neoplasm, such as an adenoma or an adenocarcinoma. The expression profiles of the present invention are useful in a range of applications including, but not limited to, those relating to the diagnosis and/or monitoring of colorectal neoplasms, such as colorectal adenomas and adenocarcinomas. Further disclosed are methods of screening a subject for the onset, predisposition to the onset and/or progression of a large intestine neoplasm by screening for modulation in the expression profile of the disclosed nucleic acid molecule markers.

Method of diagnosing neoplasms

Growing community of inventors

Malvern, Australia

Graeme P Young