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Huels Aktiengesellschaft

Graciella Djavid

Marcel Jozefowicz

Peter Ottersbach

Frank F Hill

Jean-Pierre Vairon

Veronique Migonney

By Regina Luise Hill

By Friedrich Frank Hill

The invention relates to water-insoluble polymers which promote cell proliferation, contain carboxylate and sulfonate groups and are obtainable by free radical copolymerization of one or more aliphatically unsaturated monomers containing carboxylate groups, or the correspondingly functionalized derivatives of the monomers, as component I with one or more aliphatically unsaturated monomers containing sulfonate groups, or the correspondingly functionalized derivatives of the monomers, as component II and a component III which comprises an aliphatically unsaturated monomer or several aliphatically unsaturated monomers, the correspondingly functionalized derivatives being converted into carboxylate and sulfonate groups after the copolymerization, and to a process for their preparation, wherein the polymers are useful for forming articles which promote cell proliferation.

Carboxylate-sulfonate polymers

Preparation of carboxylate-sulfonate polymers having cell proliferation-promoting properties

The invention relates to water-insoluble, bacteriophobic and optionally cell proliferation-inhibiting polymers obtainable by free-radical polymerization of (a) at least one monomer of the general formula R&mdash;(A),, in which R is an aliphatically unsaturated organic radical with the valence a, A is a carboxyl group &mdash;COOH, sulfuric acid group &mdash;OSO,OH, sulfonic acid group &mdash;SO,H, phosphoric acid group &mdash;OPO(OH),, phosphonic acid group &mdash;PO(OH),, phosphorous acid group &mdash;OP(OH),, a phenolic hydroxyl group or a salt of one of the groups, and a is 1, 2 or 3, with the proviso that, if the monomer of the formula I contains a carboxyl group &mdash;COOH or a carboxylate group, either this monomer contains at least one further radical A having a different one of the definitions specified for A, or at least one further monomer of the formula I is also used in which A has a different one of the definitions specified for A; and (b) at least one other aliphatically unsaturated monomer, wherein the polymers are useful for forming bacteriophobic or cell proliferation-inhibiting articles.

Water insoluble bacteriophobic polymers containing carboxyl and sulfonic acid groups

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Paris, France

Graciella Djavid