Buckman Laboratories International, Inc.

Other

Graciela H Vunk

Thomas E McNeel

Marilyn S Whittemore

Stephen D Bryant

David Oppong

Richard A Clark

Russel E Fues

Richard D Lusk, Jr

Luis Zugno

William C Ganus

Deborah A Marais

Thomas E Mcneel

Richard D Lusk

Luis A Zugno

Jr Richard D Lusk

The present invention provides a method of treating an aqueous system for biocide control, by adding an acidified solution that includes monoalkyldithiocarbamate salt and alkyl isothiocyanate to an aqueous system. A biocide feed system is also provided that is configured to generate a reproducible level of alkyl isothiocyanate. The method and system provide effective levels of alkyl isothiocyanate for rapid biocidal activity, along with levels of monoalkyldithiocarbamate salt which can decompose to form additional alkyl isothiocyanate and provide longer-term biocidal activity.

Method and apparatus for the enhancement of the biocidal efficacy of monoalkyldithiocarbamate salts

A method for killing, preventing, or inhibiting the growth of microorganisms in an aqueous system or on a substrate capable of supporting a growth of microorganisms is provided by providing lysozyme, alone or in combination with a quaternary ammonium compound to the aqueous system or substrate.

Lysozyme-based method and composition to control the growth of microorganisms in aqueous systems

Methods and compositions controlling biofouling using sulfamic acids

The invention relates to a method to inhibit bacteria from adhering to a submergible surface. The method contacts the submergible surface with an effective amount of at least one sulfamic acid or salt thereof to inhibit bacterial adhesion to the submergible surface. The invention also relates to a method for controlling biofouling of an aqueous system. This method adds an effective amount of at least one sulfamic acid or salt thereof to inhibit bacteria from adhering to a submerged surface within the aqueous system. This method effectively controls biofouling without substantially killing the fouling organisms. The sulfamic acid used in the method of the invention has the formula R.sup.1 R.sup.2 NS(O).sub.2 (OH). In this formula, R.sup.1 and R.sup.2 are independently a hydrogen, a C.sub.4 -C.sub.20 alkyl group or a cyclohexyl group. However, R.sup.1 and R.sup.2 are not both hydrogen. Alternatively, R.sup.1 and R.sup.2, together with the N, may also form a 5-8 membered heterocyclic ring having the formula: ##STR1## In the heterocyclic ring, X is O, NH, or CH.sub.2. The salt of sulfamic acid can be an acid salt or quaternized sulfamic acid salt. The present invention also relates to a composition containing sulfamic acids or salts thereof useable in the above methods. The compositions comprise at least one sulfamic acid or salt thereof in an amount effective to inhibit bacteria from adhering to submergible or submerged surfaces.

Methods for controlling biofouling using sulfamic acids

The invention relates to a method to inhibit bacteria from adhering to a submergible surface. The method contacts the submergible surface with an effective amount of at least one amino methyl phosphonic acid or salt thereof to inhibit bacterial adhesion to the submergible surface. The invention also relates to a method for controlling biofouling of an aqueous system. This method adds an effective amount of at least one amino methyl phosphonic acid or salt thereof to inhibit bacteria from adhering to a submerged surface within the aqueous system. This method effectively controls biofouling without substantially killing the fouling organisms. The amino methyl phosphonic acid used in the methods of the invention has the formula R.sup.1 R.sup.2 NCH.sub.2 P(O)(OH).sub.2. In this formula, R.sup.1 and R.sup.2 are independently a C.sub.6 -C.sub.20 alkyl group or a CH.sub.2 P(O)(OH).sub.2 group. However, R.sup.1 and R.sup.2 are not both a CH.sub.2 P(O)(OH).sub.2 group. Alternatively, R.sup.1 and R.sup.2, together with the N, may also form a 5-8 membered heterocyclic ring having the formula: ##STR1## In the heterocyclic ring, X is O, NH, or CH.sub.2. The salt of an amino methyl phosphonic acid can be an acid salt or a quaternized amino methyl phosphonic acid salt. The invention also relates to a composition containing amino methyl phosphonic acids or salts thereof and useable in the above methods. The compositions comprise at least one amino methyl phosphonic acid or salt thereof in an amount effective to inhibit bacteria from adhering to submergible or submerged surfaces.

Methods for controlling biofouling using amino methyl phosphonic acids

Compositions comprising an ionene polymer and a pyrithione salt are disclosed which are synergistically effective compared to the respective components alone in controlling the growth of microorganisms in or on a material or medium. Methods to control the growth of microorganisms and prevent spoilage caused by microorganisms with the use of the compositions of the present invention are also disclosed.

Synergistic antimicrobial compositions containing an ionene polymer and

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Como, MS, United States of America

Graciela H Vunk