Verenium Corporation

Basf Enzymes LLC

Illumina Corporation

Illumina Cambridge Limited

Sequenom, Inc.

Basf Se Corporation

Other

Bp Corporation North America Inc.

Grace DeSantis

Mark Joseph Burk

Jay Milton Short

Dan Eric Robertson

David Paul Weiner

Kelvin Wong

Aileen Milan

Kelly Chatman

Ellen Chi

Jennifer Ann Chaplin

Mark Madden

Robert Farwell

Sylke Haremza

Janne Samuli Kerovuo

Ryan T McCann

Oliver Koch

Andrew Slatter

Tilo Habicher

Stephen M Gross

Jian-Sen Li

Charles Cantor

Mathias Ehrich

Peter Luginbuhl

Samantha Snow

Natalie Morrell

Reinhold Mueller

Darcy Madden, Legal Representative

Kevin Shen

Connie Jo Hansen

Shaun Healey

Geoff Hazlewood

David Blum

Brian R Morgan

Alexander Varvak

Thomas Todaro

Kristine Chang

Charles Hancock

Thomas Woodward

Bob Farwell

David B Weiner

Hwai Wen Chang

Toby Howard Richardson

Lishan Zhao

Tim S Hitchman

David M Weiner

Scott Beaver

Junhua Zhao

William H Greenberg

Zuolin Zhu

Sarah R Hanson

Oliver Jon Miller

Zoulin Zhu

Patti Kretz

Marcy Madden, Legal Representative

Scott W Beaver

Hwai Chang

Peter Luginbühl

Hayley Marianne Hogan

Ryan Mccann

This disclosure describes a hybridization buffer including a crowding agent, a method that includes using the hybridization buffer, and a kit including the hybridization buffer. This disclosure also describes blockers for use in hybrid capture methods, methods of using those blockers, and a kit including those blockers. Additionally, this disclosure describes a method of hybrid capture that does not include amplifying the library members using PCR prior to sequencing the library members.

Compositions and methods for improving library enrichment

The present disclosure relates to methods, compositions, and kits for treating target nucleic acids, including methods and compositions for fragmenting and tagging nucleic acid (e.g., DNA) using transposome complexes bound to a solid support.

Tagmentation using immobilized transposomes with linkers

Technology provided herein relates in part to methods, processes and apparatuses for non-invasive assessment of genetic variations.

Methods and processes for non-invasive assessment of genetic variations

The invention relates to nitrilases and to nucleic acids encoding the nitrilases. In addition methods of designing new nitrilases and method of use thereof are also provided. The nitrilases have increased activity and stability at increased pH and temperature.

Nitrilases, nucleic acids encoding them and methods for making and using them

Provided herein are isolated laccase enzymes and nucleic acids encoding them. Also provided are mediators for laccase reactions. Also provided herein are methods for using laccases to oxidize lignins, other phenolic, and aromatic compounds, such as for bio-bleaching and decolorization of wood pulp under high temperature and pH conditions to facilitate a substantial reduction in use of bleaching chemicals, as well as for treatment of fibers.

Laccases for bio-bleaching

Provided herein are isolated laccase enzymes and nucleic acids encoding them. Also provided are mediators for laccase reactions. Also provided herein are methods for using laccases to oxidize lignins and other phenolic and aromatic compounds, such as for bio-bleaching and decolorization of wood pulp under high temperature and pH conditions to facilitate a substantial reduction in use of bleaching chemicals, as well as for treatment of fibers.

The invention relates to enzymes having xylanase, mannanase and/or glucanase activity, e.g., catalyzing hydrolysis of internal &#x3b2;-1,4-xylosidic linkages or endo-&#x3b2;-1,4-ghicanase linkages; and/or degrading a linear polysaccharide beta-1,4-xylan into xylose. Thus, the invention provides methods and processes for breaking down hemicellulose, which is a major component of the cell wall of plants, including methods and processes for hydrolyzing hemicelluloses in any plant or wood or wood product, wood waste, paper pulp, paper product or paper waste or byproduct. In addition, methods of designing new xylanases, mannanases and/or glucanases and methods of use thereof are also provided. The xylanases, mannanases and/or glucanases have increased activity and stability at increased pH and temperature.

Xylanases, nucleic acids encoding them and methods for making and using them

Nitrilases

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San Diego, CA, United States of America

Grace DeSantis