Hoechst Roussel Pharmaceuticals

Other

Hoechst Marion Roussel

Gordon E Olsen

Larry A Davis

Richard C Effland

Joseph T Klein

Grover C Helsley

Brian S Freed

Russell R Hamer

Kevin J Kapples

Peter A Nemoto

David G Wettlaufer

James W Boyd

Thomas R Boyd

An image display device includes a case with an opening, a luminous source image display displaying a first image, and a focusing element. The focusing element is positioned within the case, and includes a concave mirror and a mirror supporter that supports the concave mirror. The mirror supporter includes a mirror cradle. The mirror screen is mounted on the arms of the mirror cradle. The mirror cradle includes a buffering pad at the tip of each arm, and the buffering pad includes adhesive parts on both surfaces. The tip of the arms of the mirror cradle is attached to the back of the mirror screen, and the attachment is achieved with a surface contact. The mounting holes on the top and bottom plates are oblong. The oblong mounting holes are adapted to adjust the mounting position of the mirror screen of the image display device.

Image display device

This invention relates to compounds of the formula ##STR1## where R.sub.1 -R.sub.6, X and Y are as defined in the specification, which are useful for the treatment of various memory dysfunctions characterized by a cholinergic deficit and thus may be indicated in the treatment of Alzheimer's disease.

Carbamoyl-1-(pyridinylalkyl)-1H-indoles, indolines and related analogs

This application relates to a process for the preparation of indolylpyridooxazines of the formula ##STR1## wherein R.sub.1, R.sub.2 and R.sub.3 are as defined in the specification which comprises cyclizing compound of the formula ##STR2## in the presence of a strong base such as sodium hydride or potassium t-butoxide.

Synthesis of pyridooxazinyl-indoles

There are described compounds of the formula ##STR1## where n is 0 or 1;

Certain nitro-3-pyrinamines and 3-oxy-analogues

This invention relates to 1-(pyrido[3,4-b]-1,4-oxazinyl-4-yl)-1H-indoles of the formula ##STR1## where R.sub.1 -R.sub.3 are as defined herein which are useful for alleviation of depression and various memory dysfunction characterized by a cholinergic or adrenergic deficit. This invention also relates to intermediate compounds of the formula ##STR2## where R.sub.1, R.sub.2, R.sub.3, R.sub.7 and X are as defined herein.

N-(halopyridin-4-yl)-N-substituted compounds as intermediates in the

Heteroarylamino- and heteroaryloxypyridinamines and related compounds

This invention relates to compounds of the formula ##STR1## wherein R.sub.1 is hydrogen, loweralkyl, arylloweralkyl, loweralkenyl or loweralkynyl;

1-(pyridinylalkyl)-1H-indoles, indolines and related analogs

This invention relates to compounds of the formula ##STR1## wherein

1-(pyrido[3,4-b]-1,4-oxazinyl-4-yl)-1H-indoles and intermediates for the

1-Carbonyl derivatives of 4-pentafluorophenoxypiperidines and methods for treating convulsions, depression, and hypertension utilizing compounds or compositions thereof are disclosed.

1-substituted-4-pentafluorophenoxypiperidines

Carbonyl derivatives of 4-pentafluorophenoxypiperidines and methods for treating convulsions, depression, and hypertension utilizing compounds or compositions thereof are disclosed.

1-subsituted-4-pentafluorophenoxypiperidines

This invention relates to N-heteroaryl-4-pyrimidinamines of the formula ##STR1## where R.sub.1 is hydrogen, loweralkyl, aryl, or arylloweralkyl; R.sub.2 and R.sub.3 are independently hydrogen or loweralkyl, or R.sub.2 and R.sub.3 taken together are aryl; R.sub.4 and R.sub.5 are independently hydrogen or loweralkyl, or R.sub.4 and R.sub.5 taken together are aryl; X is hydrogen, halogen, cyano, nitro, amino, loweralkyl, loweralkoxy, trifluoromethyl or ##STR2## where Y is hydrogen, halogen or loweralkyl; m is an integer of 1 to 3; and the pharmaceutically acceptable acid addition salts thereof and where applicable the geometrical and optical isomers and racemic mixtures thereof. The compounds of this invention display utility as memory enhancing agents and as analgesic agents.

N-substituted-4-pyrimidinamines and pyrimidinediamines

There are disclosed various compounds of the formula below, ##STR1## where n is 0 or 1;

1-(substituted pyridinylamino)-1H-indol-5-yl substituted carbamates

There are disclosed compounds of the formula, ##STR1## wherein m, n, p, R, R.sub.1, R.sub.2 and R.sub.3 are as defined in the specification; which compounds are useful for enhancing memory and also as analgesic and antidepressant agents.

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Somerset, NJ, United States of America

Gordon E Olsen