Accuray Inc.

Gopinath Kuduvalli

Dongshan Fu

Eric Earnst

Michael J Saracen

Calvin R Maurer

John W Allison

Calvin R Maurer, Jr

John Robinson Dooley

Adam Jerome Weber

Prashant Chopra

Petr Jordan

Sohail Sayeh

James Y Wang

Aaron W Carrano

Mu Young Lee

Chris Raanes

Christopher A Raanes

Euan Thomson

Shehrzad Ahmed Qureshi

Matthew Core

Hongwu Wang

William T Main

Mohan Bodduluri

Jay Bailey West

Bai Wang

Zhiping Mu

Hui Zhang

Derek Olender

Robert D Khan

Paul Dennis Treas

Jian Gao

Warren Kilby

Sankaralingam Ramraj

George Asmerom

Warren D Kilby

Jin-Wu J Wang

Hendricus J Wolters

Daniel Brown

Vladimir Mitrovic

Kenneth W Schulze

Michael J Stratford-Collins

Monica A Condit

Matthew A Core

James Wang

A treatment couch with a localization array is described.

Treatment couch with localization array

A method of operating a localization array. The method includes providing the localization array in substantially an optimal position. The method also includes maintaining the localization array at substantially the optimal position by controlling movement of the localization array.

Localization array position determination in a treatment room coordinate system is described. A method may include imaging, using an imaging system, a position of one or more markers integrated with a localization array in a treatment room and transforming the position of the one or more markers to a treatment room coordinate system. The method also includes determining the position of the localization array in the treatment room coordinate system based on the transforming.

Localization array position in treatment room coordinate system

Methods of two-dimensional x-ray imaging of a target volume and tracking a target structure contained within a target volume are described.

Two-dimensional x-ray imaging of a target volume

Tracking a target structure contained within a target volume using an x-ray tomosynthesis imaging detector is described.

Tracking a target structure contained within a target volume using an X-ray tomosynthesis imaging detector

An IGRT system and methods are described embodiments of which perform selectively integration of x-ray source arrays, dual-energy imaging, stereoscopic imaging, static and source collimation, or inverse geometry tomosynthesis imaging to acquire or track a target during radiation treatment.

Imaging methods for image-guided radiation treatment

Fiducial localization methods and apparatus are described.

Fiducial localization

Treatment targets such as tumors or lesions, located within an anatomical region that undergoes motion (which may be periodic with cycle P) are tracked. A 4D mathematical model may be established for the non-rigid motion and deformation of the anatomical region, from a set of CT or other 3D images. The 4D mathematical model relates the 3D locations of part(s) of the anatomical region with the targets being tracked, as a function of the position in time within P. Using non-rigid image registration between pre-operative and intra-operative images, the position of the target and/or other part(s) of the anatomical region may be determined.

Tracking of moving targets

An apparatus includes a portion that moves along a guided path and a displacement gauge that outputs readings based on the portion's position on the guided path. The apparatus additionally includes an intermediate limit switch that is activated in response to the portion being moved to an intermediate position on the guided path. The apparatus also includes a processing device configured to calibrate the apparatus based on a first reading corresponding to a first position on the guided path and a second reading corresponding to a second position on the guided path. The processing device verifies the calibration based on a third reading corresponding to the intermediate position.

Automatic calibration for device with controlled motion range

Treatment targets such as tumors or lesions, located within an anatomical region that undergoes motion (which may be periodic with cycle P), are dynamically tracked. A 4D mathematical model is established for the non-rigid motion and deformation of the anatomical region, from a set of CT or other 3D images. The 4D mathematical model relates the 3D locations of part(s) of the anatomical region with the targets being tracked, as a function of the position in time within P. Using fiducial-less non-rigid image registration between pre-operative DRRs and intra-operative x-ray images, the absolute position of the target and/or other part(s) of the anatomical region is determined. The cycle P is determined using motion sensors such as surface markers. The radiation beams are delivered using: 1) the results of non-rigid image registration; 2) the 4D model; and 3) the position in time within P.

Dynamic tracking of moving targets

Systems, methods, and related computer program products for image-guided radiation treatment (IGRT) are described. For one preferred embodiment, an IGRT apparatus is provided comprising a gantry frame including a ring member, the ring member being rotatable around a substantially horizontal, longitudinally extending central axis, the ring member having first and second horizontally opposing ends. The IGRT apparatus further comprises a radiation treatment head coupled to the ring member by an arm member, the arm member being connected to the ring member at an arm member base. Preferably, the IGRT apparatus is further characterized in that the arm member extends outwardly from the first end of the ring member in a direction away from the second end and is supported only by the arm member base, and the radiation treatment head is dynamically movable in at least a longitudinal direction toward and away from the first end of the ring member.

Radiation treatment delivery system with outwardly movable radiation treatment head extending from ring gantry

An automatic collimator changer of a radiation treatment system.

Collimator changer

Systems, methods, and related computer program products for medical imaging and image-guided radiation treatment (IGRT) are described. In one embodiment, an IGRT system selectively integrates x-ray source arrays, dual-energy imaging, stereoscopic imaging, static and dynamic source collimation, and/or inverse geometry tomosynthesis imaging to acquire and/or track a target during radiation treatment. Advantages include reduced patient x-ray dose and/or reduced treatment delivery margins.

A robotic treatment delivery system including a linear accelerator (LINAC), and a robotic arm coupled to the LINAC. The robotic arm is configured to move the LINAC along at least four rotational degrees of freedom and one substantially linear degree of freedom.

Robotic arm for a radiation treatment system

Growing community of inventors

San Jose, CA, United States of America

Gopinath Kuduvalli