Battelle Memorial Institute

Gokhan Yavas

Brian A Young

Esley M Heizer

Daniel M Bornman

Nancy McMillan

Angela T Minard-Smith

Jr Esley M Heizer

Jr Heizer Esley M

Nancy J McMillan

Nancy J Mcmillan

In at least one illustrative embodiment, a method may comprise selecting a first plurality of text strings that each represent a nucleotide sequence that was read by a massively parallel sequencing instrument, where the nucleotide sequences represented by the selected first plurality of text strings each correspond to a first target locus, comparing the selected first plurality of text strings to one another to determine an abundance count for each unique text string included in the selected first plurality of text strings, identifying a first number of unique text strings included in the selected first plurality of text strings as representing noise responses, and determining a method detection limit as a function of the abundance counts for the first number of unique text strings identified as representing noise responses.

Methods of analyzing massively parallel sequencing data

Growing community of inventors

Columbus, OH, United States of America

Gokhan Yavas