The Salk Institute for Biological Studies

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Christopher J Lamb

Peter W Doerner

A novel transcription enhancer element (AATT) , that increases the activity of cis-elements in heterologous promoter constructs without altering their intrinsic specificity is provided. Also provided is a transcription factor, PABF, which specifically binds to the (AATT) repeat element and methods of use therefor.

Method of increasing transcription with nucleic acids encoding PABF

A novel transcription enhancer element, (AATT),, that increases the activity of cis-elements in heterologous promoter constructs without altering their intrinsic specificity is provided. Also provided is a transcription factor, PABF, which specifically binds to the (AATT) repeat element and methods of use therefor.

Purified palindromic element binding factor

A novel transcription enhancer element, (AATT).sub.n, that increases the activity of cis-elements in heterologous promoter constructs without altering their intrinsic specificity is provided. Also provided is a transcription factor, PABF, which specifically binds to the (AATT) repeat element and methods of use therefor.

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Wein, Austria

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