Advinus Therapeutics Private Limited

Gobind Sing Kapkoti

Venkata Poornapragnacharyulu Palle

Debnath Bhuniya

Bhavesh Dave

Kasim A Mookhtiar

Siddhartha De

Sujay Basu

Sandeep Bhausaheb Bhosale

Keshav Naik

Santosh Kurhade

Anil M Deshpande

Balasaheb Kobal

Sachin Kandalkar

Anita Chugh

Debanath Bhuniya

Anil Deshpande

Compounds of the present disclosure are 2,2,2-tri-substituted acetamide derivatives of formula (I), its polymorphs, stereoisomers, prodrugs, solvates, pharmaceutically acceptable salts and formulations thereof, useful as Glucokinase activator. 

2,2,2-tri-substituted acetamide derivatives as glucokinase activators, their process and pharmaceutical application

Acetamide derivatives, their stereoisomers, tautomers, prodrugs, pharmaceutically acceptable salts, polymorphs, solvates and formulations thereof for the prophylaxis, management, treatment, control of progression, or adjunct treatment of diseases and/or medical conditions where the activation of glucokinase would be beneficial, are disclosed.  The disclosure also provides process of preparation of these acetamide derivatives.

Acetamide derivatives as glucokinase activators, their process and medicinal application

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Maharashtra, India

Gobind Sing Kapkoti