Toray Industries, Inc.

Soda Aromatic Co., Ltd.

Go Hata

Masato Mutoh

Hideyuki Hashimoto

Hideki Kawai

Masaji Ohno

Tatsuya Kaneko

Masanobu Naruto

Hisao Kondo

Toshifumi Shirakawa

Keiichi Matsunaga

Satoshi Hanada

Takeaki Etoh

Takashi Uchiyama

Yuji Matsuura

A platinum(II) complex represented by the general formula (A), ##STR1## in which R.sub.1 represents a hydrocarbon radical having 1 to 10 carbon atoms, R.sub.2 and R.sub.3 each represent a hydrogen atom or a hydrocarbon radical of 1 to 10 carbon atoms, or R.sub.2 and R.sub.3, together, may form --(CH.sub.2).sub.4 -- or --(CH.sub.2).sub.5 --, and X and Y each represent an ammonia molecule or a monodentate amine having 1 to 7 carbon atoms or X and Y, together, may form a bidentate diamine having 2 to 10 carbon atoms. The compounds are useful for treating a tumor.

Platinum(II) complex and antitumor agent

Platinum (II) complex and agent for treating malignant tumor

A platinum complex represented by the formula: ##STR1## where X is ##STR2## wherein R.sup.1 is a (C1-18) alkyl group, a (C1-18)alkenyl group or a group --Z--R.sup.4 in which Z is --CH.dbd.CH-- or a (C1-5)alkylene group, and R.sup.4 is a phenyl group, a hydroxyphenyl group, a (C7-12)alkoxyphenyl group, a halogenophenyl group, a nitrophenyl group, or (C8-13)alkoxycarbonylphenyl group, a cyclohexyl group having a (C1-5)alkyl substituent, ##STR3## R.sup.2 is hydrogen or a (C1-18)alkyl group, R.sup.3 is hydrogen or a (C1-3) alkyl group, R.sup.2 and R.sup.3 are linked together to form a (C2-7)alkylene group; the dotted line indicates that the bond may be either a single bond or a double bond; the chain line indicates a conjugated system; the 1,2-diaminocyclohexane moiety has a cis-, trans-l- or trans-d-configuration; and Y is an anion. This platinum complex is useful in the treatment of tumors.

Platinum complex, process for preparing same and antitumor agent

Preparation of angelic acid or esters thereof

Provided is a perfume composition containing a straight-chain trans-6-alkenoic acid represented by the general formula ##STR1## wherein n is an integer of 1 to 4.

Perfume composition containing an unsaturated aliphatic carboxylic acid

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Fujisawa, Japan

Go Hata