Noramco Gmbh

Purisys, Inc.

Gnel Mkrtchyan

Wen-Chun Zhang

Denis Petrovic

Jasper Kaiser

Daniel M Hallow

Martin Benedict Strack

Mark C Dobish

Jun He

The present disclosure relates to the preparation of a highly pure cannabidiol compound by a novel synthesis route. The cannabidiol compound can be prepared by an acid-catalyzed reaction of a di-halo olivetol with menthadienol, followed by two crystallization steps. The highly pure cannabidiol compound is produced in high yield, stereospecificity, or both, and shows exceedingly low levels of Δ-9-tetrahydrocannabinol at the time of preparation and after storage.

Cannabidiol compositions having modified cannabinoid profiles

The present disclosure relates to the preparation of methyl 2-(1H-indole-3-carbonyl)thiazole-4-carboxylate (ITE) and related compounds with high yield, purity, and scalability. The processes apply the use of a Weinreb amide intermediate as a scaffold for the preparation of ITE and structural analogs.

Processes for the preparation of aryl hydrocarbon receptor ligands

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Watkinsville, GA, United States of America

Gnel Mkrtchyan