Medical Development Tehcnologies S.a.

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Nv Thermocore Medical Systems Sa

Thermocore Medical Systems Nv

Glenn Van Langenhove

Bruno Schwagten

Leonidas Diamantopoulos

Stewart Maddison Fox

The present invention concerns a self-expanding implant device comprising a proximal portion at a first longitudinal end, a distal portion at a second longitudinal opposite the first longitudinal end, and a connecting portion between the proximal portion and the distal portion, wherein the proximal portion and the distal portion each comprise a radially self-expanding structure, wherein the connecting portion comprises longitudinally oriented bendable struts, preferably at least 4 struts, more preferably 6 struts or more, which connect the self-expanding structure of the proximal portion with the self-expanding structure of the distal portion, wherein in a fully expanded state, the implant device comprises a maximum implant diameter along a direction perpendicular to the longitudinal direction and wherein the struts of the connecting portion comprise a strut length along the longitudinal direction, characterized in that the strut length is such that when the self-expanding structure of the proximal portion is in a compacted state and the self-expanding structure of the distal portion is not constrained radially, the self-expanding structure of the distal portion reaches a semi-expanded state comprising a diameter which is at least 60% of the maximum implant diameter.

Implant stent device

The current invention concerns systems, devices and methods for the ablation of a ablation of the wall of one or more pulmonary veins (PV) from the inside, preferably transmural ablation and preferably at the level of the antrum. Hereby, one or more implant devices can be implanted in the vessels and can subsequently be heated by external energy-providing means.

Implant device and system for ablation of a vessel's wall from the inside

The current invention concerns systems, devices and methods for the ablation of a vessel's wall from the inside, more specifically to implant devices and to the ablation of the wall of one or more pulmonary veins (PV) from the inside, preferably transmural ablation and preferably at the level of the antrum. Hereby, one or more implant devices can be implanted in the vessels and can subsequently be heated by external energy-providing means.

System, device and method for ablation of a vessel's wall from the inside

In a first aspect, the current invention concerns a computer-implemented method, system and computer program product for identifying a zone in a blood vessel system with a risk level for stasis, comprising the following steps: a) providing an angiogram of a blood vessel system, said angiogram comprising a time series of images of said blood vessel system, at least some of said images showing a contrast agent present in said blood vessel system; b) identifying at least one zone within said blood vessel system on a multitude of images of said time series; c) characterising variations in greyscale intensity in said zone across at least part of said time series of images; d) characterising an outflow of said contrast agent from said zone on the basis of said variations in intensity in said zone; and e) providing a local risk level for stasis in said zone. In further aspects, the current invention also concerns a computer-implemented method, system and computer program product for identifying a zone in a blood vessel with a risk level for stenosis and stent malpositioning, and for measuring the coronary flow reserve (CFR).

Computer-implemented method for identifying zones of stasis and stenosis in blood vessels

The current invention concerns systems, devices and methods for the ablation of a vessel's wall from the inside, more specifically to implant devices and to the ablation of the wall of one or more renal arteries from the inside, preferably transmural ablation. Hereby, one or more implant devices can be implanted in the vessels and can subsequently be heated by external energy-providing means.

Implant device and system for ablation of a renal arterial wall from the inside

The invention is based on the realisation that inflamed plaques in blood vessel walls, which are potentially vulnerable to rupture, can be detected at elevated temperatures which are lower than previously realised. In particular, the low temperatures at which inflamed plaque can be detected are often associated with systems in which blood flow is generally close to normal in particular temperature differences above zero but not more than 0.39&#xb0; C. have been found to be indicative of the presence of inflamed plaque.

Determining vulnerable plaque in blood vessels

The present invention provides a catheter apparatus for temperature measurement of vascular tissue, comprising a flexible body, at least one resiliently biased projection depended from the body, a sensor carried by the projection and an electrical carrier for transmitting data from the sensor to a remote device, wherein the projection, in a deployed configuration, adopts an arcuate shape along at least part of its length, wherein the gradient of the arcuate portion of the projection, with respect to the longitudinal axis of the catheter, increases as a function of distance along the projection from the end attached to the catheter body.

Biased vascular temperature measuring device

The present invention provides a vascular catheter apparatus for temperature measurement of vascular tissue, comprising a flexible body, at least one resiliently biased projection depended from the body, a sensor carried by the projection and an electrical carrier for transmitting temperature data at the vascular wall from the sensor to a remote device. The electrical carrier may be coiled around the length of the projection to reduce the strain at critical points where it is necessary to maintain a seal and hence electrical isolation.

Growing community of inventors

Merelbeke, Belgium

Glenn Van Langenhove