Commonwealth Scientific and Industrial Research Organisation

Clinical Genomics Pty. Ltd.

Glenn Southwell Brown

Peter Laurence Molloy

Susanne Kartin Pedersen

Lawrence Charles Lapointe

Robert Dunne

Graeme P Young

Lloyd Douglas Graham

Lawrence Clarence Lapointe

Disclosed are nucleic acid, RNA, and protein expression profiles which are indicative of the onset, predisposition to the onset and/or progression of a large intestine neoplasm. More particularly disclosed are nucleic acid molecules, the expression profiles of which are indicative of the onset and/or progression of a colorectal neoplasm, such as an adenoma or an adenocarcinoma. The expression profiles of the present invention are useful in a range of applications including, but not limited to, those relating to the diagnosis and/or monitoring of colorectal neoplasms, such as colorectal adenomas and adenocarcinomas. Further disclosed are methods of screening a subject for the onset, predisposition to the onset and/or progression of a large intestine neoplasm by screening for modulation in the expression profile of the disclosed nucleic acid molecule markers.

Method of diagnosing neoplasms

Growing community of inventors

Epping, Australia

Glenn Southwell Brown