Igen, Inc.

Igen International, Inc.

Other

Surendera K. Tyagi

Steve Woodward

Glenn Zoski

Lee O. Hall

Glenn D Zoski

Jonathan K Leland

Jack E Goodman

John T Grosser

Ali Ghaed

Lee O Hall

Surendera K Tyagi

Ali Ghead

An apparatus as provided for use in carrying out electrochemiluminescence test measurements. The apparatus includes a fluid container having an inlet for introducing an electrochemiluminescence sample fluid and a fluid outlet. The fluid container is composed of a durable, transparent, chemically inert, and electrically nonconductive material. A working electrode is disposed to one side of a fluid flow path of the container which has a light transmissive wall opposite the working electrode. A counter electrode is secured to the light transmissive wall. A first portion of the counter electrode is disposed upstream of the working electrode, while a second portion of the counter electrode is disposed downstream of the working electrode.

Instrument incorporating electrochemiluminescent technology

An apparatus is taught for carrying out electrochemiluminescent measurements which includes a working electrode and a temperature sensor. The electrochemiluminescent measurements made by the apparatus are adjusted based upon the measured temperature.

Apparatus for carrying out electrochemiluminescence test measurements

An apparatus for agitating an electrochemiluminescent test sample in a sample container having a mouth for permitting withdrawal of the electrochemiluminescent test sample therefrom and a body extending away from the mouth. The apparatus includes a base, a first member movably mounted with respect to the base and including a first engaging mechanism for engaging the body of the sample container at a first position, and a second member fixedly mounted with respect to the base and including a second engaging mechanism for engaging the body of the sample container at a second position between the first position and the mouth thereof. In this apparatus, a first motive mechanism is provided for moving the first member so that at least a portion of the sample container adjacent to the first position thereof together with the electrochemiluminescent test sample therein is agitated in response to the motion of the first member.

Apparatus and methods for carrying out electrochemiluminescence test

An apparatus for conducting electrochemiluminescence test measurements consisting of a fluid container having a fluid flow path, a first counter electrode positioned within the fluid container directly secured to a transparent mounting block and having an electrode surface exposed to fluids within the fluid flow path, a working electrode with an electrode surface being displaced from the electrode surface of the first counter electrode laterally with respect to the flow direction of fluid within the fluid flow path.

An apparatus for conducting measurements of electrochemiluminescence including a movable sample container support in the form of a carousel having a plurality of spaced apart support positions, an electrochemiluminescence testing device, a motor system to move the sample container support in a predetermined sequence, a sample transfer device to transfer sample from containers in the support positions to the testing device, and a detection system to detect the presence of a sample container and to produce an actuation signal based on the detected presence of the sample container.

An apparatus as provided for use in carrying out electrochemiluminescence test measurements. The apparatus includes a cell to contain an electrochemiluminescence sample fluid. A working electrode is provided within the cell and is coupled to a supply of electrical energy to apply the same to the sample fluid. A temperature effect adjustment system serves either to adjust a temperature of the electrochemiluminescent sample fluid so that it is within a predetermined range, or else adjusts an output signal representing light produced through electrochemiluminescence of the sample fluid based on the temperature of the sample fluid.

A method and apparatus for triggering and measuring electrochemiluminescent phenomena using a voltage waveform applied at the voltammetric working electrode which improves the precision and accuracy of measurements. This waveform has a decreasing scan rate in the range of voltages for which electrochemiluminescence is triggered and is substantially sinusoidal in shape in this range. The waveform results from locating the reference electrode of a potentiostat in close potential proximity to its counter electrode, and applying a uniform scanning voltage waveform at the reference electrode. The waveform also can be synthesized digitally, converted to analog form, and applied directly to the working electrode with the reference electrode in close potential proximity to the working electrode.

Method and apparatus for conducting electrochemiluminescent measurements

An apparatus for conducting measurements of electrochemiluminescent (ECL) phenomena includes a cell unit having an electrode configuration for inducing the emission of ECL light by the application of a selected voltage waveform to a sample fluid including an ECL moiety. The sample fluid is transported to and from the cell unit by a flow-through pump/tubing system. A photomultiplier tube detects the intensity of light emitted by the sample fluid during the ECL measurement process. A computer control unit both analyzes the detected data and provides digital control signals to the cell unit to generate effective voltage waveforms. The digital control signals are supplied to a novel pulse width modulated digital to analog converter which outputs a ramp voltage waveform having the desired slope.

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Vienna, VA, United States of America

Glenn D Zoski