University of Florida Research Foundation Inc

Glenn A Walter

Swadeshmukul Santra

Brij M Moudgil

Huabei Jiang

Edward William Scott

Parvesh Sharma

Stephen R Grobmyer

Scott Chang Brown

Qizhi Zhang

Niclas Bengtsson

Paul Howard Holloway

Robert A Mericle

Heesun Yang

Multimodal nanoparticles are nanoparticles containing contrast agents for PAT and one or more of luminescence imaging, x-ray imaging, and/or MRI. The multimodal nanoparticles can have a dielectric core comprising an oxide with a metal coating on the core. The particles can be metal speckled. The multimodal nanoparticles can be used for therapeutic purposes such as ablation of tumors or by neutron capture in addition to use as contrast agents for imaging.

Multimodal nanoparticles for non-invasive bio-imaging

The present invention relates to fluorescent, radio-opaque and magnetic quantum nanoparticles, useful as multifunctional contrast agents or probes for in vivo bioimaging, and methods of their use. The invention provides for multifaceted bioimaging (e.g., intra-arterial pre-operative brain mapping and broad based in vivo diagnostic imaging), including imaging of various cell types, such as stem cells.

Nanoparticles and their use for multifunctional bioimaging

Growing community of inventors

Newberry, FL, United States of America

Glenn A Walter