Qbiotics Pty Ltd

Qbiotics Limited

Glen Mathew Boyle

Paul Warren Reddell

Victoria Anne Gordon

Peter Gordon Parsons

Ryan Moseley

Robert Steadman

Rachael Louise Moses

Jason Kingsley Cullen

David William Thomas

Lydia Charlotte Powell

Manon F Pritchard

Katja Etel Hill

The present invention relates to methods of treating tumours comprising the localised administration, for example, intratumourally or topically, of an epoxytiglienone compound (as a monotherapy) to cancerous tumours to generate a systemic anticancer abscopal (anenestic) and/or bystander effect.

Method of treating tumours

The present invention relates to a combination therapy for tumours comprising the administration of an epoxytigliane compound and an immune checkpoint inhibitor. In particular embodiments, there is a method of treating a tumour and/or treating or preventing one or more bystander tumours with the therapy. Pharmaceutical compositions and kits containing epoxytigliane compounds and immune checkpoint inhibitors are also described.

Combination therapy for the treatment or prevention of tumours

The present invention relates to epoxy-tigliane compounds and their use in promoting wound healing. In particular embodiments, the epoxy-tigliane compounds are epoxy-tigliaen-3-one compounds. Methods of inducing or promoting wound healing as well as methods of reducing scarring and improving cosmetic outcomes upon healing of a wound are described. Compounds and compositions for use in wound healing are also described.

Methods and compositions for wound healing

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Taringa, Australia

Glen Mathew Boyle