University of London

Albert-ludwigs-universitaet Freiburg

L'oreal

Agency for Science, Technology and Research

Agresearch Limited

Massey University

Albert-ludwigs-universitat Freiburg

Gleb Sukhorukov

Toni Cathomen

Tatjana Cornu

Jamal Alzubi

Irina Nazarenko

Dong Luo

Yana Tarakanchikova

Valentina Pennucci

Michael Cattel

Saroash Shahid

Andrew Greaves

Harjinder Singh

Maxim Kiryukhin

Maria Antipina

Nicole Roy

Qiangying Yi

Brendan Haigh

Marina Novoselova

Jordan Elise Read

Jiaxin Zhang

David James Gould

Valeriia Kudriavtceva

The present invention relates to a biodegradable multilayer nanocapsule for the delivery of at least one biologically active agent into at least one target cell consisting of at least two layers of at least two biodegradable polymers which are laid one onto the other and whereby the biologically active agent is layered onto a layer of a biodegradable polymer and covered with a further layer of a biodegradable polymer, whereby one biologically active agent is a nucleic acid.

Biodegradable multilayer nanocapsules for the delivery of biologically active agents in target cells

The present invention provides a crystalline salt of chlorhexidine chloride having a spherical morphology under Scanning Electron Microscopy (SEM) comprising a chloride anion and a cation selected from the group consisting of calcium, sodium, potassium, magnesium, zinc, strontium or iron, processes for the preparation of the salt, compositions, pharmaceutical compositions and uses thereof in medicine. Also provided are crystalline forms of the salt and fibres comprising the same.

Chlorhexidine crystal forms and uses thereof in medicine

Disclosed herein is a core-shell composite material comprising: a core optionally comprising an active ingredient compound; a shell structure comprising at least two alternating layers; the alternating layers being a protein layer and a polyphenol layer; and optionally a polyelectrolyte layer interfacing said core and said shell structure, said polyelectrolyte layer being disposed adjacent to said protein layer or said polyphenol layer, wherein said shell structure is selected to be resistant to degradation under gastric conditions but is degradable by one or more intestinal enzymes. In a preferred embodiment the protein is bovine serum albumin (BSA) or pepsin, the polyphenol layer is tannin or tannic acid, and the shell structure is degradable by pepsin.

Core-shell composite material

The invention relates to capsules of core/shell type, the core comprising an active agent; the shell comprising one or more concentric and alternating layers of a first photosensitive anionic amino polymer and of a second cationic polymer. The invention also relates to a cosmetic or pharmaceutical composition comprising such capsules. The invention also relates to a non-therapeutic cosmetic process for treating keratin materials, comprising the application to the keratin materials of a cosmetic composition comprising the said capsules, followed by exposure of the deposit formed on the keratin materials to natural light or to artificial light with a wavelength of between 360 and 600 nm.

Photosensitive capsules and cosmetic and pharmaceutical use thereof

Growing community of inventors

London, United Kingdom

Gleb Sukhorukov