Basf Aktiengesellschaft

Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara Rt.

Gizella Miholics

Gyula Sebestyen

Marton Fekete

Frigyes Gorgenyi

Katalin Marmarosi

Istvan Simonyi

Pal Vago

Marta Kovacs

Istvan Seres

Maria Szeli

Anna Z Szabo

Marta Kovcas

Egri Janos

Joszef Gaal

The invention relates to a stabile, aqueous suspoemulsion containing as active ingredient 0.2-5 weight % of primycin, 5-25 weight % of propylene glycol, 0.5-5 weight % of non-ionic surface active agent, if desired 15 weight % of auxiliary agent and distilled water in an amount necessary to 100 weight %, as well as to a process for the preparation thereof.

Pharmaceutical composition and process for the preparation thereof

The invention refers to a novel pharmaceutical composition having especially antimycotic activity and comprising the zinc complex of 5-chloro-7-iodo-8-hydroxyquinoline of formula (I) ##STR1## and one or more pharmaceutically acceptable carriers. The pharmaceutical composition of the invention can be used for the effective treatment of mycotic infections on the skin surface, mucous membranes or nails. The complex of formula (I) is prepared by reacting a solution of an alkali metal salt of 5-chloro-7-iodo-8-hydroxyquinoline with a solution containing an excess of an inorganic or organic zinc salt or a zinc complex having a lower stability constant than that of the complex of formula (I) and separating the product precipitated.

Pharmaceutical composition comprising an organic zinc complex and a

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Budapest, Hungary

Gizella Miholics