Chiron S.r.l.

Other

Giuseppe Teti

Luciano Polonelli

Franco Felici

Peptides that mimic the antigenic features of non human-cross-reactive protective epitopes of the MenB CP and nucleic acids encoding the peptide mimetics are disclosed. Antibodies elicited by these peptides do not bind to polysialic acid in host tissue and thus provide a safe and efficacious method for the treatment and/or prevention of Meningitis B.

Peptides that mimic non-human cross-reactive protective epitopes of the group B meningococcal capsular polysaccharide

The invention relates to peptide, oligopeptide or polypeptide compounds that are capable of eliciting a protective immune response against the capsular polysaccharide of group(GBS), particularly type III GBS. Such compounds are useful in the development of vaccines that are effective against diseases caused by these pathogens.

Vaccine formulations comprising antiidiotypic antibodies which immunologically mimic group B streptococcal carbohydrates

The invention relates to peptide, oligopeptide or polypeptide compounds that are capable of eliciting a protective immune response against the capsular polysaccharide of group B Streptococcus (GBS), particularly type III GBS. Such compounds are useful in the development of vaccines that are effective against diseases caused by these pathogens.

Growing community of inventors

Messina, Italy

Giuseppe Teti