Politecnico Di Milano

Consiglio Nazionale Delle Ricerche

Cambridge Enterprise Limited

Fondazione Istituto Italiano Di Tecnologia

Universitá Degli Studi Di Milano-Bicocca

Fondazione Cariplo

Fondazione Cassa Di Risparmio Delle Province Lombarde

Giulio Cerullo

Dario Polli

Roberto Osellame

Manuela Teresa Raimondi

Antonio Perri

Fabrizio Preda

Andrea Carlo Ferrari

Cristian Angelo Manzoni

Gianluca Valentini

Andrea Bassi

Claudio Conci

Tommaso Zandrini

Giuseppe Chirico

Jürgen Hauer

Andrea Remuzzi

Daniel Popa

Tullio Scopigno

A laser device comprises a first optical cavity comprising a first gain medium and a second optical cavity comprising a second gain medium. The first gain medium and the second gain medium generate light at respective different ranges of wavelengths. A synchronizer is optically coupled to both the first optical cavity and the second optical cavity and is configured to synchronize and mode-lock light from the first optical cavity and the second optical cavity. The laser device also includes a first optical filter and a second optical filter to filter the light from the first optical cavity and the second optical cavity respectively to output first filtered light pulses at a first predetermined range of wavelengths and second filtered light pulses at a second predetermined range of wavelengths.

Laser device

A Fourier-transform hyperspectral imaging system may include an optical imaging system configured to produce an image of an object, and an adjustable birefringent common-path interferometer module comprising a movable birefringent element and configured to produce interfering replicas of an input radiation which are delayed from each other by a phase delay adjustable by the moving birefringent element. The interferometer module may be configured to produce collinear replicas for entering optical rays parallel to said optical axis. The hyperspectral imaging system further comprises a two-dimensional light detector configured to receive the replicas and provide digital images of the object depending on said adjustable phase delay. The system also includes an analysis device configured to perform a Fourier Transform of the digital images to obtain a hyperspectral representation of the object.

Fourier-transform hyperspectral imaging system

An implantable medical device obtained by means of two-photon laser polymerisation of a resin to form a three-dimensional matrix, wherein: said three-dimensional matrix comprises a number of levels distributed in height; and said three-dimensional matrix comprises reference means designed to uniquely identify the height of each level from a pre-set reference, by means of a multi-photon fluorescence-excitation microscope; said implantable medical device being characterised in that said reference means comprise a solid having a cross section that varies with height.

Implantable medical device

A measurement system of photoluminescence properties of a sample, comprises a radiation source module configured to generate a first radiation, an excitation optical path coupled to the radiation source module, a support structured to support a sample to be optically coupled to excitation optical path and adapted to provide a photoluminescence radiation, and collection path coupled to the sample and configured to propagate the photoluminescence radiation. The system also includes an analysis device configured to receive the photoluminescence radiation and provide data/information on photoluminescence properties of sample. At least one path between the excitation path and the collection path comprises a respective adjustable birefringent common-path interferometer module configured to produce first and second radiations adapted to interfere with each other.

Birefringent interferometer for measuring photoluminescence properties of samples

The present invention relates to a supermatrix of synthetic niches comprising at least two matrices of niches wherein each matrix comprises n&#xd7;m niches and wherein the distance (d) between a matrix and the other is greater than zero and wherein in each matrix every synthetic niche has one or more walls in common with the others synthetic niches of the matrix. A support for the culture of cells that includes at least one supermatrix and the use of said supermatrix or support for the in vitro culture of cells, in particular stem cells, or for the in vivo implant in a subject in order to promote tissue or organ regeneration through cell repopulation are also within the scope of the present invention.

Synthetic niche matrices for stem cell culture

Growing community of inventors

Milan, Italy

Giulio Cerullo