Merck Patent Gesellschaft MIT Beschraenkter Haftung

Giuliano Dolce

Eike Poetsch

Jurgen Uhl

Helmut Muller-Calgan

Wighard Strehlow

Dieter Marx

3-Fluoro-2,3-dihydro-1H-1,4-benzodiazepin-2-ones of the formula ##STR1## wherein R.sup.1 is H, alkyl or fluorinated alkyl of 1-4 carbon atoms and up to 9 fluorine atoms or cycloalkylalkyl of 4-8 carbon atoms; R.sup.2 is phenyl; monohalophenyl or pyridyl; R.sup.3 is F, Cl, Br or NO.sub.2, and physiologically acceptable acid addition salts thereof, are central nervous system depressants.

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Giuliano Dolce