Ciba-geigy Corporation

Imperial Chemical Industries Limited

Macleod Pharmaceuticals, Inc.

Giovanni Parrinello

Rolf Mulhaupt

Hubert Simon

David Thorpe

Gabriel Verhelst

Mireille B De Witte

Julian Francis Hopper

Rolf Muhaupt

A liquid pharmaceutical solution having antimicrobial agent(s), an organic solvent, and an acidic or basic aqueous medium therein. Most preferred solutions include trimethoprim, sodium hydroxide, sulfadiazine, N-methylpyrrolidone and water. The present invention is also directed toward making these solutions. A most preferred composition includes: trimethoprim in an amount of about 40 mg/ml of liquid pharmaceutical solution; sulfadiazine in an amount of about 200 mg/ml of liquid pharmaceutical solution; N-methylpyrrolidone in an amount of about 514 mg/ml of liquid pharmaceutical solution, sodium hydroxide in an amount of about 30 mg/ml of liquid pharmaceutical solution and water. Methods of making the pharmaceutical solution preferably include combining the following in any order: trimethoprim, N-methylpyrrolidone, sulfadiazine, and an acidic or basic aqueous medium. Other additives, such as antioxidants and preservatives, can also be added to the liquid pharmaceutical solution.

Pharmaceutical solution and methods for preparation thereof

Process for recycling flexible foams by glycolysis and extraction. The glycolysis is conducted by allowing the foam to react with low molecular weight polyols, then allowing the mixture to separate in two phases.

Recycling of flexible foam

The level of unsaturation in certain polyols can be reduced by extraction with certain low molecular weight polyols like ethylene glycol.

Process for reducing unsaturation on polyols

Compounds of general formula I ##STR1## wherein R.sup.2 is hydrogen unsubstituted C.sub.1 -C.sub.6 alkyl or C.sub.1 -C.sub.6 alkyl substituted by --OH, --CN or by --Si(OR.sup.3).sub.3-q R.sup.4.sub.q, or C.sub.2 -C.sub.6 alkenyl,

Organosilane aminals and aminal adducts

Novel iminosilanes of the general formula Ia or Ib ##STR1## in which R.sub.1 is alkyl, cycloalkyl or aralkyl containing at least on the .alpha.-C atom substituents which are inert towards isocyanate groups, so that no hydrogen atom is present on this C atom, R.sub.2 is as defined for R.sub.1 or is hydrogen, or R.sub.1 and R.sub.2 , together with the common C atom, form a cyclohexylene ring which has on the two C atoms substituents which are inert towards isocyanate groups, R.sub.3 to R.sub.7 are organic radicals, p is 0,1 or 2, m is 1 or 2, n is an integer from 1 to 5 and X is --S-- or --NH--, are described.

Iminosilanes

Compounds of the general formula I ##STR1## wherein R.sub.1 is hydrogen, C.sub.1 -C.sub.12 alkyl, C.sub.5 -C.sub.7 cycloalkyl, phenyl or benzyl,

Moisture curable polyurethane resin having a compound or an oxazolidine

Compounds of the general formula I ##STR1## wherein R.sub.1 is a hydrogen, C.sub.1 -C.sub.12 alkyl, C.sub.5 -C.sub.7 cycloalkyl, phenyl or benzy.,

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Duisburg, Belgium

Giovanni Parrinello