Inalco S.p.a.

Basf Se Corporation

Ritter Pharmaceuticals, Inc.

Inalco S.r.l.

Fresenius Kabi Austria Gmbh

Inalco S.a.s. Di Giovanni Cipolletti & C.

Tenagro S.r.l.

Giovanni Cipolletti

Liana Salsini

Marco Manoni

Luana Vagnoli

Jacopo Chini

Gessica Laudati

Michael Puhl

Giorgio Zoppetti

Pasqua Anna Oreste

Debora Bartalucci

Giancarlo Tamerlani

Ilaria Lombardi

Silvia Biagiolini

Silvia Giacomelli

Renato Carobbi

Sandro Miletti

Giuseppe Bimbi

Andrea Danesi

Rosanna Abbate

Maria Anna Gori

Marina Matulli

Barbara Febbruari

Sonia Spagnesi

The present invention describes a syrup of tagatose and galactose as main components together with other secondary products such as glycerol, oligosaccharides and other sugars in a minority amount.

Tagatose and galactose syrup

The present invention describes a process for the production of (&#x2212;)-cannabidiol (CBD) from industrial hemp by means of an extraction followed by two alternative working processes: a process A which provides extraction with solvents first to an alkaline pH and then to acidic pH to isolate the carboxyl form of the CBD which is then subjected to decarboxylation and a process B which provides the elimination of waxes and pitches and then purification by chromatography. At the end of both alternative working processes the CBD is crystallized obtained in high purity crystalline form.

Method for the production of cannabinoids from types of industrial hemp

This invention describes new hydrated and anhydrous polymorphs of 2'-O-fucosyllactose (2&#x2032;FL): Polymorph A 2&#x2032;FL-3/2HO, Polymorph B 2TL-5/2 HO and anhydrous Polymorph C. There is also a description of the methods for obtaining them, and of a new method for preparing Polymorph I already known in the literature.

Hydrated and anhydrous polymorphs of 2'-O- fucosyllactose and their production methods

The present invention describes a process for preparing ultrapure (&#x2265;95%) galacto-oligosaccharides (GOS), starting from GOS at lower purities by using sequential microbiological purifications involvingand

Process for the production of ultrapure galacto-oligosaccharides

Hydrated and anhydrous polymorphs of 2'-O-fucosyllactose and their production methods

This invention describes new hydrated and anhydrous polymorphs of 2'-0-ficosyllactose (2&#x2032;FL): Polymorph A 2&#x2032;FL-3/2HO, Polymorph B 2TL-5/2HO and anhydrous Polymorph C. There is also a description of the methods for obtaining them, and of a new method for preparing Polymorph I already known in the literature.

This invention describes new hydrated and anhydrous polymorphs of 2'-0-fucosyllactose (2&#x2032;FL): Polymorph A 2&#x2032;FL-3/2HO, Polymorph B 2TL-5/2 HO and anhydrous Polymorph C. There is also a description of the methods for obtaining them, and of a new method for preparing Polymorph I already known in the literature. 

The present invention describes a process for preparing ultrapure (&#x2267;95%) galacto-oligosaccharides (GOS), starting from GOS at lower purities by using sequential microbiological purifications involvingand

The present invention relates to a process of synthesis of &#x3b1;-sialyl oligosaccharides and in particular of 6'-sialyllactose and its salts comprising a step of coupling by Koenigs-Knorr reaction under conditions that allow its use on an industrial scale.

6'-sialyllactose salts and process for their synthesis and for the synthesis of other alpha-sialyloligosaccharides

The present invention concerns a process that can be realised continuously for the preparation of anhydrous crystalline lactulose from commercial aqueous syrups that contain it, characterised in that the crystallisation and consequent separation of the high-purity lactulose with high yields from the syrup is triggered by mixing the ore pulp (or recycled ore pulp), obtained from a previous lactulose crystallisation phase, with the syrup itself.

Continuous process for the preparation of crystalline lactulose

The present invention relates to a process for industrially producing tagatose starting from galactose and provides for chemical isomerisation in presence of XAlOand XOH (with X=Na, K) and microbiological purification of the residual galactose.

Tagatose preparation

A process is described for the preparation of N-Acetyl-D-mannosamine monohydrate of formula (I) a specific intermediate in the synthesis of N-Acetyl-neuraminic acid, that is an important starting product for the synthesis of various pharmaceutically active products. 

Process for the preparation of N-Acetyl-D-mannosamine monohydrate

The present invention relates to a process for the preparation of sulphated glycosaminoglycans derived from N&#x2014; acetylheparosan which comprises: a) N-deacetylation and N-sulphation of the N-acetylheparosan polysaccharide prepared from natural or recombinant bacterial strain, preferably K5, b) enzymatic epimerization with the glucuronyl C5-epimerase enzyme, c) partial O-sulphation followed by a partial O-desulphation, d) partial 6-O-sulphation, e) N-sulphation and an intermediate step of controlled depolimerization characterised by the fact that both O-sulphations (O-sulphation and 6O-sulphation) are partial. Furthermore the invention relates to the products obtained according to the process which show a ratio between the anti-Xa activity and anti-IIa activity equal to or higher than 1 and to compositions comprising said products in combination with suitable and pharmaceutically acceptable excipients and/or diluent.

Polysaccharide derivatives with high antithrombotic activity in plasma

The present invention refers to the preparation of O-sulphated, N-sulphatated or N-acetylated derivatives, both epimerised or non epimerised, of K5, K4, and optionally defructosilated K4 and K40 polysaccharides and to their use as antiinflammatory agents in chronic and acute inflammations.

O-sulphated bacterial polysaccharides and their use

The present invention relates to a new process in 3 steps starting from 2-C-methyl-D-ribopentono-1,4-lactone for the preparation of tetra-acyl ribofuranose derivatives of formula (I):useful in the synthesis of nucleotides.

Growing community of inventors

Milan, Italy

Giovanni Cipolletti