Rhone Poulenc Agriculture Limited

Alexion Pharmaceuticals, Inc.

Gillian Mary Little

Susan Mary Cramp

Paul A Cain

Claude Lambert

Derek Ian Wallis

John Morris

Simon Neil Pettit

David Alan Roberts

Keith Clinch

Philip H Smith

Jean-Paul Bulot

Thomas David Yarwood

Brian Malcolm Luscombe

Tibor Musil

Andreas Brunner

Rachel Anne Dixon

Danmei Dai

Cyrille Abel Sébastien Landreau

Nicolas Georges Rene Proisy

Derek Kevin Watt

Xiangtian Long

Sylvia Myrna Baars

Provided herein are synthetic methods for preparing a compound of formula (I): Also provided herein are synthetic methods for preparing a compound of formula (XIII): The disclosure also provides useful intermediates, derivatives, prodrugs, and pharmaceutically acceptable salts, solvates and hydrates of the formula (I) and formula (XIII) compounds. These compounds are useful for treating diseases associated with molybdenum cofactor deficiency.

Methods for synthesizing molybdopterin precursor Z derivatives

Herbicides derived from 2-cyano-1,3-diones have the formula: ##STR1## wherein R, R.sup.1, R.sup.2 R.sup.3, R.sup.4 and R.sup.5 are as defined in the description. The compounds are intended for use pre- and post-emergence as selective herbicides in maize and a large number of other monocotyledon crops.

Herbicidal 2-cyano-1,3-diones

The invention relates to 4-substituted isoxazole derivatives of formula I: ##STR1## wherein R, R.sup.1, R.sup.2, Q and n have the meanings defined in the description, which possess valuable herbicidal properties.

Herbicidal 4-substituted isoxazoles

The invention relates to 4-benzoylisoxazole derivatives of formula (I): ##STR1## wherein: R represents the hydrogen atom or a group --CO.sub.2 R.sup.4 ;

4-benzoylisoxazole herbicides

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Essex, United Kingdom

Gillian Mary Little