Johnson & Johnson Surgical Vision, Inc.

Gilles Vandewiele

Guang-ming Dai

Benjamin Straker

Jeroen Van Der Donckt

Michael Rademaker

Joshua Young

Described are implementations of systems and methods for an improved machine learning-based system that incorporates pre-operative and intraoperative measurements captured during surgery, as well as additional patient-specific data, to provide an individualized, highly accurate post-operative manifest refraction prediction. According to some embodiments, a determination engine generates a predictive feature set of one or more predictors associated with diagnostic measurements of one or more eyes and performs a recursive selection operation using one or more combinations within the predictive feature set and one or more models to produce a most predictive subset, the most predictive subset having a highest prediction accuracy among other predictive subsets for post-operative manifest refraction. The determination engine generates a determination model by refining and retraining the one or more models of the recursive selection operation utilizing the most predictive subset.

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Ghent, Belgium

Gilles Vandewiele