Boehringer Ingelheim International Gmbh

Boehringer Ingelheim Pharma Gmbh & Co Kg

Gilbert Wuttke

Joachim Eicher

Bernd Zierenberg

Andreas Fiol

Jens Besseler

Hubert Kunze

Johannes Geser

Holger Holakovsky

Michael Schyra

Herbert Graessl

Alexander Bach

Dieter Hochrainer

Heinrich Kladders

Matthias Hausmann

Andree Jung

Stephen Terence Dunne

Herbert Wachtel

Martin Meisenheimer

Robert Gerhard Winkler

Manuel Krakowka

Alfred Von Schuckmann

Ralf Thoemmes

Ying Yu

Stefan Kaulmann

Klaus Noehl

Mike Janetzko

Manuel Daelman

Elmar Mock

Antonino Lanci

Horst Wergen

Andre Klopfenstein

Hubert Hoelz

Achim Moser

Frank Herrmann

Josef Gatz

Christoph Dworzak

Joerg Schiewe

Markus Mast

Joachim Carl Herbert Eicher

Markus Mueller

Guido Schmiedel

Christian Golberg

Markus Kaemper

Jochen Ziegler

Martin Essing

Josef Eckert

Antonio Lanci

Thomas Wabnitz

Ralf Thömmes

Udo Frenkel

Joachim Karl Herbert Eicher

Herbert Graessel

A cartridge and a nebulizer for nebulizing a fluid as well as a method for fluidically connecting the cartridge to the nebulizer are proposed. The cartridge comprises a closure with a valve, wherein the valve displaces fluid into the nebulizer when opened. Further, the cartridge forms two axially spaced sealings with the nebulizer when connected.

Nebulizer and cartridge

A method for producing a cartridge is proposed, where a fluid is filled into an opening of a container and a closure part is inserted into the container, thereby moving a movable piston arranged within the container.

Method for producing a cartridge

A nebulizer for nebulizing a fluid from a cartridge and a cartridge for such a nebulizer is proposed. The cartridge comprises a container containing the fluid to be nebulized and is fluidically connected to the nebulizer by inserting a connecting element of the nebulizer for conveying the fluid out of the container. The cartridge is preferably adapted to sealingly receive the connecting element and can optionally comprise a membrane or sealing wall which seals the cartridge initially and is piercable or breakable by the connecting element upon insertion. The cartridge can further comprise an at least partially flexible and/or bendable tube for conveying the fluid out of the container. The tube is preferably wettable with the fluid and/or comprises an at least partially hydrophilic and/or polar surface. Further, the tube can at least partially be shaped as a helix. When the cartridge is connected to the nebulizer, the tube and the connecting element preferably form a continuous capillary and/or an at least essentially constant flow area.

A container, a nebulizer and a use of an indicator device are described, where the container comprises an indicator device fixedly mounted on the bottom of the container, the container is arranged within the nebulizer and the container can be detached by grabbing the indicator device.

Container, nebulizer and use

A nebulizer as well as a container and an indicator device for such a nebulizer are proposed. The indicator device is fixedly mounted from the bottom of the container and comprises a piercing element for opening an aeration of the container. The indicator device and its piercing part are preferably actuated by axial movement of the indicator device and container within the nebulizer.

Container, indicator device with moveable piercing part, and nebulizer

A nebulizer includes an insertable container and a securing mechanism for holding the container in the nebulizer such that the container can move back and forth but cannot be separated. The securing mechanism is formed by a metal unitary part. The securing mechanism forms a transportation lock for holding the container unmovable in the housing in a delivery state of the nebulizer. The securing mechanism forms a cage which encompasses the container.

Nebulizer

A nebulizer and a container with a fluid for such a nebulizer are described, the container comprising an indicator device fixedly mounted on the bottom of the container, the indicator device stopping further use of the container in a locked state when a predetermined number of uses has been reached or exceeded, and when the nebulizer is partially opened, it is blocked against further use, and after replacement of the container including the indicator device, the nebulizer can be used again.

A nebulizer is proposed which includes an insertable container and a securing mechanism for holding the container in the nebulizer such that the container can move back and forth but can not be separated. The securing mechanism is formed by a metal unitary part. The securing mechanism forms a transportation lock for holding the container unmovable in the housing in a delivery state of the nebulizer. The securing mechanism forms a ring with flexible holding fingers.

A nebulizer includes an insertable container and a counter device for counting operations of the nebulizer. The nebulizer can be opened for replacing the container. The counter devices blocks opening of the nebulizer until a predetermined number for operations has been reached.

A device, cartridge and method for dispensing a liquid, preferably a drug, are proposed. The liquid is pressurized in a cartridge to a first lower pressure and, then, pressurized in doses by a pump to a second higher pressure. A valve arranged between the cartridge and the pump is normally closed and/or opened only temporarily. Thus, evaporation and dripping of liquid can be avoided or minimized.

Device, cartridge and method for dispensing a liquid

A nebulizer having an insertable container and a monitoring device for counting actuations of the nebulizer is proposed. The monitoring device is mounted in a detachable housing part and directly detects movements of container during a nebulizing process, an air supply current in the region of a mouthpiece, and/or the production of aerosol, in order to detect this as the actual dispensing of fluid and actuation of the nebulizer, while preferably the time of actuation of the nebulizer is additionally detected and stored. This allows better monitoring and guidance for the user.

A nebulizer includes an insertable container and a securing mechanism for holding the container in the nebulizer such that the container can move back and forth but can not be separated. The securing mechanism is formed by a metal unitary part. The securing mechanism forms a transportation lock for holding the container unmovable in the housing in a delivery state of the nebulizer. The securing mechanism forms a cage which encompasses the container.

An inhaler () is proposed (see FIG.), for the inhalation of a formulation () from capsules () that each contain one dose of the formulation. The capsules are preferably each emptied in a capsule chamber () by being set in motion by a stream of air flowing through the capsule chamber. The stream of air can be generated by the inhalation of a user or patient and/or can be generated actively generated by the inhaler. For simple handling, the inhaler has a means for, in particular, automatic filling, emptying and/or cleaning of the capsule chamber, if the latter is used more than once. Alternatively, the inhaler has a large number of capsule chambers that each preferably already contain a capsule and re preferably used just once.

Inhaler

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Dortmund, Germany

Gilbert Wuttke